CIRCOUTCOMES: April 29, 2013 Background—Prior studies found that only about half of stroke patients arrived at hospitals via emergency medical services (EMSs), yet since then, there have been efforts to increase public awareness that time is brain. Using contemporary Get With the Guidelines-Stroke data, we assessed nationwide EMS use by stroke patients. Read more
Stroke: April 4, 2013 The pharmaceutical industry is in the doldrums. Food and Drug Administration drug approvals per year are falling steadily,1 and the costs of drug development are steadily increasing.2 However, although neuroscience as a whole may not be delivering the returns on investment we would like, the state of stroke medicine has never been better. Although […]
Springer Link: April 1, 2013 BACKGROUND Even though medications can greatly reduce the risk of recurrent stroke, medication adherence is suboptimal in stroke survivors. OBJECTIVE To identify key barriers to medication adherence in a predominantly low-income, minority group of stroke and transient ischemic attack (TIA) survivors. DESIGN Cross-sectional study. PARTICIPANTS Six hundred stroke or TIA […]
STROKEAHA: April 18, 2013 Background and Purpose—Acute intraprocedural thrombus formation complicating endovascular cerebral aneurysm treatment is often treated with intra-arterial or intravenous administration of thrombolytic agents or glycoprotein IIb/IIIa (GpIIb/IIIa) inhibitors. We sought to evaluate the morbidity and mortality associated with such treatments using a large multihospital database. Methods—Using the Premier Perspective Database, we examined outcomes […]
International Journal of Stroke: April 17, 2013 Background and Aims Body temperature, inflammation, and infections may modify response to thrombolytic therapy. We studied their associations with clinical improvement after intravenous thrombolysis and three-month outcome. Methods We included 985 consecutive acute ischemic stroke patients treated with intravenous thrombolysis at the Helsinki University Central Hospital during 1995–2008. […]
J Am Heart Assoc.: April 15, 2013 Background It is uncertain how intracranial stenting (ICS) has been adopted nationally during a period characterized by a restrictive payment policy by the Centers for Medicare & Medicaid Services, humanitarian device exemption approval by the Food and Drug Administration, and insufficient evidence of effectiveness. We sought to determine the […]
J NeuroIntervent Surgery: April 12, 2013 Background and purpose Treatment of intracranial fusiform aneurysms is complex and controversial, and is associated with high morbidity and mortality rates. The goal of this study was to evaluate the strategy of stent only therapy. Materials and methods A retrospective analysis of 20 patients with 20 intracranial fusiform aneurysms undergoing endovascular […]
J NeuroIntervent Surgery: April 11, 2012 Background Recent evidence indicates that multidisciplinary care improves patient outcomes in cerebrovascular (CV) disease. A multidisciplinary integrated CV program was recently instituted at a high-volume tertiary referral center, providing the opportunity to evaluate patient outcomes before and after its introduction. Objective To evaluate outcomes after treatment of patients with intracranial aneurysm in […]
The Lancet Neurology: April 1, 2013 Little is known about the pathophysiology of intracerebral haemorrhage that occurs during anticoagulant treatment. In observational studies, investigators have reported larger haematoma volumes and worse functional outcome in these patients than in those with intracerebral haemorrhage and a normal coagulation status. The need to prevent extensive haematoma enlargement by rapid […]
J NeuroIntervent Surgery: March 29, 2012 Background and objective Flow diverters are an exciting new class of endovascular devices that treat aneurysms by curative reconstruction of the parent artery. The Pipeline embolization device (PED) is the first FDA-approved intracranial flow diverting device available in the USA. This paper presents periprocedural results with the device in a series […]
