A carving method to determine an optimal working projection using three-dimensional volume rendering digital subtraction angiography in coil embolization of cerebral aneurysms

J NeuroIntervent Surgery: February 28, 2012 Background A working projection in coil embolization of a cerebral aneurysm is usually determined using three-dimensional volume rendering digital subtraction angiography (3D VRDSA), in which the boundary between an aneurysm and its parent artery cannot be identified simultaneously on the front and back surfaces of the vessel. A new method was […]

Thrombolysis Despite Recent Stroke

STROKEAHA: April 2, 2013 Background and Purpose—Thrombolysis in ischemic stroke is contraindicated in patients who have had a stroke within 3 months. However, it is unclear whether thrombolytic therapy is associated with adverse outcomes in this population. We report the characteristics and outcomes of patients treated with systemic recombinant tissue-type plasminogen activator in the context of […]

Studies Probe Restoring Speech in Persons With Chronic Stroke-Related Aphasia

JAMA: March 27, 2013 During the 30 years Ana Inés Ansaldo, PhD, practiced as a speech and language therapist, she frequently encountered patients who, after being silenced by stroke-related aphasia for many years, were able to utter everyday words or link words into spoken sentences. As a scientist, Ansaldo wanted to find out why elderly individuals […]

Joint Commission Primary Stroke Centers Utilize More rt‐PA in the Nationwide Inpatient Sample

J Am Heart Assoc.: March 26, 2013 Background The Joint Commission began certifying primary stroke centers (PSCs) in December 2003 and provides a standardized definition of stroke center care. It is unknown if PSCs outperform noncertified hospitals. We hypothesized that PSCs would use more recombinant tissue plasminogen activator (rt‐PA) for ischemic stroke than would non‐PSCs. Methods and […]

Efficacy of Coupling Inhibitory and Facilitatory Repetitive Transcranial Magnetic Stimulation to Enhance Motor Recovery in Hemiplegic Stroke Patients

STROKEAHA: March 26, 2013 Background and Purpose—Although there has been extensive research on the effectiveness of repetitive transcranial magnetic stimulation (rTMS) to improve patients’ motor performance after experiencing chronic stroke, explicit findings on the coupling of different rTMS protocols are meager. We designed this sham-controlled randomized study to investigate the potential for a consecutive suppressive-facilitatory TMS […]

Why Calls for More Routine Carotid Stenting Are Currently Inappropriate

STROKEAHA: March 19, 2013 To avoid misguidance from calls for more routine practice (nontrial) carotid angioplasty/stenting (CAS), we need to distinguish relevant facts and patients’ best interests from all else (distractions). A recent editorial by White and Jaff1 is one publication which illustrates this need particularly well. First, these authors are correct in reminding us that the […]

Remote Limb Preconditioning and Postconditioning

STROKEAHA: January 22, 2013 Preconditioning is an adaptive process of endogenous protection in which small, sublethal doses of a harmful agent protect the organism against a later lethal dose of the same agent. The basic principle is evident in human thought and literature, encapsulated in Nietzsche’s statement, “what does not kill me makes me stronger.”1 Ischemic preconditioning, […]

Efficacy and safety of warfarin vs. antiplatelet therapy in patients with systolic heart failure and sinus rhythm: a systematic review and meta-analysis of randomized controlled trials

International Journal of Stroke: March 19, 2013 Background and purpose Heart failure is an independent risk factor for stroke. Anticoagulation is effective for prevention of cardio-embolic stroke secondary to atrial fibrillation or mechanical heart valves but is of uncertain benefit in heart failure patients. We performed this meta-analysis to obtain the best estimates of the […]

Stent-Assisted Coiling of Intracranial Aneurysms

STROKEAHA: March 19, 2013 Background and Purpose—Self-expanding stents are increasingly used for treatment of complex intracranial aneurysms. We assess the safety and the efficacy of intracranial stenting and determine predictors of treatment outcomes. Methods—A total of 508 patients with 552 aneurysms were treated with Neuroform and Enterprise stents between 2006 and 2011 at our institution. A […]

Lipid Profile, Lipid-lowering Medications, and Intracerebral Hemorrhage After tPA in Get With The Guidelines–Stroke

​STROKEAHA: March 14, 2013 Background and Purpose—Symptomatic intracerebral hemorrhage (sICH) after tissue plasminogen activator for acute ischemic stroke is associated with poor outcome. There are conflicting data on sICH risk related to lipid levels and use of lipid-lowering medications. We evaluated whether there are associations between lipid levels, lipid-lowering medications, and sICH in Get With the […]

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