Therapies
Friday, March 22nd, 2013
STROKEAHA: March 14, 2013 Background and Purpose—To evaluate the impact of proximal flow control on efficacy and safety of mechanical thrombectomy in an in vitro middle cerebral artery occlusion. Methods—Three independent variables, including clot type, device (Merci Retriever, Solitaire FR, and Trevo devices), and use of a balloon guide catheter, were used to ascertain the impact […]
Therapies
Thursday, March 14th, 2013
Neurology: March 13, 2013 Objective: Prominent fibrinogen cleavage by recombinant tissue plasminogen activator and formation of fibrinogen degradation products with anticoagulant properties was proposed to amplify the risk of thrombolysis-related bleeding complications, but supportive evidence mainly derived from studies on myocardial infarction. Methods: This study included 547 consecutive stroke patients treated with recombinant tissue plasminogen activator, who underwent […]
Therapies
Thursday, March 14th, 2013
Wiley: March 12, 2013 Background Race-ethnic differences may influence postthrombolysis outcomes in acute ischemic stroke patients. Guidelines for thrombolytic therapy to treat Asian stroke patients are based mostly on extrapolated western data. Aims We undertook to examine outcomes among Asians by comparing a propensity-matched cohort of thrombolyzed patients from a tertiary center in Singapore with […]
Therapies
Thursday, March 14th, 2013
Science Daily: March 11, 2013 In Europe, strokes are the most common cause of physical disability among the elderly. This often result in paralysis of one side of the body, and many patients suffer much reduced physical mobility and are often unable to walk on their own. These are the hard facts the EU project […]
Therapies
Thursday, March 14th, 2013
STROKEAHA: March 5, 2013 Background and Purpose—To investigate the relationship between severe bleeding complications and outcome after mechanical thrombectomy with or without glycoprotein-IIb/IIIa inhibitor tirofiban treatment. Methods—The study included prospectively collected data of consecutive patients with acute ischemic stroke in whom mechanical thrombectomy was perfomed in the years 2006 to 2011. Read more
Therapies
Thursday, March 14th, 2013
Wiley: February 13, 2013 Objectives Intracranial hemorrhage (ICH) after acute stroke thrombolysis is associated with poor outcomes. Previous investigations of the relationship between preexisting antiplatelet use and the safety of intravenous (IV) thrombolysis have been limited by low event rates. The objective of this study was to determine whether preexisting antiplatelet therapy increased the risk […]
Therapies
Monday, March 11th, 2013
Schattauer: March 5, 2013 Summary Patients with atrial fibrillation (AF) often receive, in addition to warfarin, antithrombotic drugs to manage other comorbid conditions. To date, few population-based studies have quantified the bleeding risk associated with the concurrent use of these therapies. The United Kingdom General Practice Research Database was used to identify a cohort of […]
Therapies
Monday, March 11th, 2013
Cardiovascular Research: March 1, 2013 Atrial fibrillation (AF) is the most common arrhythmia and one of the most vexing cardiovascular conditions for patients and the physicians who care for them. AF is a primary cause of cardioembolic stroke and may account for more than 20% of all stroke cases in older individuals.1 While AF can easily be […]
Therapies
Monday, March 11th, 2013
STROKEAHA: February 28, 2013 Background and Purpose—Endovascular therapy has increasingly become the most common treatment for unruptured cerebral aneurysms in the United States. We evaluated a national, multi-hospital database to examine recent utilization trends and compare periprocedural outcomes between clipping and coiling treatments of unruptured aneurysms. Methods—The Premier Perspective database was used to identify patients hospitalized […]
Therapies
Wednesday, March 6th, 2013
STROKEAHA: February 26, 2013 Background and Purpose—Intravenous thrombolysis for acute ischemic stroke is beneficial within 4.5 hours of symptom onset, but the effect rapidly decreases over time, necessitating quick diagnostic in-hospital work-up. Initial time strain occasionally results in treatment of patients with an alternate diagnosis (stroke mimics). We investigated whether intravenous thrombolysis is safe in these […]
