WILEY: February 22, 2013 Objective Recent economic and health policy changes may have affected the ability of chronically ill patients to afford their medications. We assessed changes in cost-related nonadherence to medication (CRN) before and after the implementation of Medicare Part D in 2006. Methods We used data from the National Health Interview Survey, an […]
STROKEAHA: February 7, 2013 On June 20 and 21, 2012, a National Institute of Neurological Disorders and Stroke-sponsored workshop on “Optimizing the Predictive Value of Preclinical Research” was held in Washington, DC.1 The primary objective of the workshop was to review deficiencies in preclinical and translational research and provide recommendations or guidelines to improve the rigor of […]
STROKEAHA: February 7, 2013 Background and Purpose—Perihematomal edema (PHE) can worsen outcomes after intracerebral hemorrhage (ICH). Reports suggest that blood degradation products lead to PHE. We hypothesized that hematoma evacuation will reduce PHE volume and that treatment with recombinant tissue-type plasminogen activator (rt-PA) will not exacerbate it. Methods—Minimally invasive surgery and rt-PA in ICH evacuation (MISTIE) […]
STROKEAHA: January 29, 2013 Each year, about 16 million people in the world experience a first-ever stroke. Of these, about 5.7 million die and another 5 million remain disabled.1 Although there are effective treatments that restore brain perfusion and minimize complications and recurrent stroke, there is no treatment proven to facilitate neurological recovery after stroke. A recent […]
Lancet Neurology: March 1, 2013 Ischaemic stroke is one of the leading causes of death and disability worldwide, and intravenous alteplase is the only proven effective treatment in the acute setting. Hypothermia has been shown to improve neurological outcomes after global ischaemia—hypoxia in comatose patients who have had cardiac arrest, and is one of the most […]
Neurology: February 13, 2013 Objectives: Data on long-term outcome after IV thrombolysis (IVT) are sparse. Our goals were to 1) estimate annual survival, and 2) evaluate determinants for an unfavorable long-term outcome after IVT for stroke. Methods: This observational study is based on the IVT registry of the University Hospital Basel. A structured telephone interview was used to […]
STROKEAHA: February 12, 2013 Background and Purpose—Despite the findings that motor imagery and execution are supposed to share common neural networks, previous studies using imagery-based rehabilitation have revealed inconsistent results. In the present study, we investigated whether feedback of cortical activities (neurofeedback) using near-infrared spectroscopy could enhance the efficacy of imagery-based rehabilitation in stroke patients. Read […]
American Heart Association: February 08, 2013 American Stroke Association Late-Breaking Science Report Report: Abstract LB 10 Embargoed until 7 a.m. HT/noon ET on Friday, Feb. 8, 2013 Study Highlights: Surgery to improve blood flow to the brain does not reverse cognitive problems associated with low blood flow in patients who have experienced a stroke or mini-stroke. […]
CIRCULATIONAHA: February 7, 2013 Background—Comprehensive stroke centers allow for regionalization of subspecialty stroke care. Efficacy of endovascular treatments, however, may be limited by delays in patient transfer. Our goal was to identify where these delays occurred and to assess the impact of such delays on patient outcome. Read more
STROKEAHA: February 6, 2013, Background and Purpose—Intravenous thrombolysis with alteplase is approved for acute ischemic stroke, but its use is limited by numerous contraindications and warnings arising from trial selection criteria or expert opinions. We examined outcomes from alteplase-treated versus untreated patients, registered in a trials archive, according to presence or absence of specified contraindications and […]
