Intravenous heparin for the treatment of intraluminal thrombus in patients with acute ischemic stroke: a case series

J NeuroIntervent Surg: 2/19/13 Abstract Background and Objectives Current American Stroke Association/American Heart Association recommendations on the management of acute ischemic stroke do not recommend the early use of heparin because of an increased risk of bleeding complications. However, for select patients, such as those with strokes associated with non-occlusive intraluminal thrombus, intravenous heparin might prove to […]

An investigation of the cost and benefit of mechanical thrombectomy for endovascular treatment of acute ischemic stroke

J NeuroIntervent Surg: 2/1/13 Abstract Introduction The use of mechanical thrombectomy for the treatment of acute ischemic stroke has significantly advanced over the past 5 years, with few available data. The aim of this study was to analyze the cost and benefit of mechanical thrombectomy devices utilized during endovascular therapy of ischemic stroke patients. Methods A retrospective chart review […]

Is Intracerebral Hemorrhage a Time-Dependent Phenomenon After Successful Combined Intravenous and Intra-Arterial Therapy?

AHA: January 31, 2013 Background and Purpose—Onset-to-reperfusion time (ORT) has recently emerged as an essential prognostic factor in acute ischemic stroke therapy. Although favorable outcome is associated with reduced ORT, it remains unclear whether intracranial bleeding depends on ORT. We therefore sought to determine whether ORT influenced the risk and volume of intracerebral hemorrhage (ICH) […]

Trends in device-assisted aneurysm treatment at a single high-volume tertiary care center

J NeuroIntervent Surg: 1/27/13 Abstract Introduction Device developments and evolution in technique over the past decade make the treatment of aneurysms which were previously considered poor candidates for coiling more feasible. The authors describe their experience treating aneurysms at a single high-volume tertiary care center, focusing particularly on the use of adjunctive devices. Methods A retrospective review was […]

Guidelines for the Early Management of Patients With Acute Ischemic Stroke

hispaniclady

AHA: January 31, 2013 A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association Background and Purpose—The authors present an overview of the current evidence and management recommendations for evaluation and treatment of adults with acute ischemic stroke. The intended audiences are prehospital care providers, physicians, allied health professionals, and hospital administrators responsible […]

Blood–brain barrier disruption is associated with increased mortality after endovascular therapy

Neurology: January 30, 2013 Objective: To evaluate the incidence, baseline characteristics, and clinical prognosis of blood–brain barrier (BBB) disruption after endovascular therapy in acute ischemic stroke patients. Methods: A total of 220 patients treated with endovascular therapy between April 2007 and October 2011 were identified from a prospective, clinical, thrombolysis registry. All patients underwent a nonenhanced CT scan […]

The THRombolysis and STatins (THRaST) study

Neurology: January 23, 2013 Objective: To assess the impact on stroke outcome of statin use in the acute phase after IV thrombolysis. Methods: Multicenter study on prospectively collected data of 2,072 stroke patients treated with IV thrombolysis. Outcome measures of efficacy were neurologic improvement (NIH Stroke Scale [NIHSS] ≤ 4 points from baseline or NIHSS = 0) and […]

Oxygen Therapy Spurs Recovery in Some Stroke Patients

Healthday: By Amanda Gardner, HealthDay Reporter – January 26, 2013 Study found certain survivors gained lost skills months, years after their attack TUESDAY, Jan. 22 (HealthDay News) — Researchers in Israel report that they harnessed the same type of therapy that helps scuba divers recover from the bends to spur recovery in stroke survivors. The treatment, known as […]

Induction of Cooling With a Passive Head and Neck Cooling Device Effects on Brain Temperature After Stroke

STROKEAHA: January 22, 2013 Background and Purpose—Therapeutic hypothermia improves clinical outcome after cardiac arrest and appears beneficial in other cerebrovascular diseases. We conducted this study to investigate the relationship between surface head/neck cooling and brain temperature. Methods—Prospective observational study enrolling consecutive patients with severe ischemic or hemorrhagic stroke undergoing intracranial pressure (ICP) and brain temperature monitoring. […]

Impact of Early Blood Pressure Variability on Stroke Outcomes After Thrombolysis

STROKEAHA: January 17, 2013 Background and Purpose—The present study determines associations between early blood pressure (BP) variability and stroke outcomes after intravenous thrombolysis. Methods—In 527 stroke patients receiving intravenous alteplase (0.6 mg/kg), BP was measured 8 times within the first 25 hours. BP variability was determined as ΔBP (maximum-minimum), standard deviation (SD), coefficient of variation, and […]

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