Therapies
Monday, October 22nd, 2012
Thrombosis Journal: October 18, 2012 Dual antiplatelet treatment with aspirin and clopidogrel is the antithrombotic treatment recommended after an acute coronary syndrome and/or coronary artery stenting. The evidence for optimal antiplatelet therapy for patients, in whom long-term treatment oral anticoagulation is mandatory, is however scarce. To evaluate the safety and efficacy of the various antithrombotic strategies […]
Therapies
Monday, October 22nd, 2012
American Heart Association, Inc.: October 15, 2012 Novel oral anticoagulants (NOACs) have been proposed as alternatives to vitamin K antagonists (VKAs) for prevention of stroke and systemic embolism (SE) in patients with atrial fibrillation (AF). Individually, NOACs were at least non-inferior to VKAs, but a clear superiority in overall and vascular mortality was not consistently proven. […]
Therapies
Monday, October 22nd, 2012
Sience Direct.: October 8, 2012 Dabigatran is a recently introduced direct thrombin inhibitor licensed for use as an oral anticoagulant for stroke prevention in non-valvular atrial fibrillation. Our prospective observational study aimed to assess the adverse effects, tolerability and patient satisfaction of dabigatran therapy in a hospital-practice population. Methods Patients starting dabigatran, after its release in […]
Therapies
Monday, October 22nd, 2012
American College of Cardiology Foundation: October 1, 2012 Year Outcomes of the Hamburg Sequential Ablation Strategy This study describes the 5-year efficacy of catheter ablation for long-standing persistent atrial fibrillation (LS-AF). Background Long-term outcome data after catheter ablation for LS-AF are limited. Methods Long-term follow-up of 56 months (range 49 to 67 months) was performed in 202 patients […]
Therapies
Monday, October 22nd, 2012
American Heart Journal: July 15, 2012. Older patients with atrial fibrillation (AF) and coronary artery disease (CAD) face high risk of stroke and bleeding with antithrombotic therapy. Balancing safe and effective use of aspirin, clopidogrel, and warfarin in this population is important. Methods From the Duke Databank for Cardiovascular Disease, we identified patients with AF […]
Therapies
Thursday, October 11th, 2012
Nature.com: 10/10/12 Substantial experimental data and recent clinical evidence suggesting that tissue reperfusion is a better predictor of outcome after thrombolysis than recanalization necessitate that patency of microcirculation after recanalization should be reevaluated. If indeed microcirculatory blood flow cannot be sufficiently reinstituted despite complete recanalization as commonly observed in coronary circulation, it may be one […]
Therapies
Thursday, October 11th, 2012
Jnis.bmj.com: 10/6/12 Introduction A number of recent trials evaluating intra-arterial therapies for acute ischemic stroke have been completed. We present a review of prospective acute ischemic stroke trials reported in a peer-reviewed forum during the last 20 years to provide insight into the general direction of this rapidly evolving field. Methods Prospective trials evaluating acute stroke intra-arterial therapies […]
Therapies
Thursday, October 11th, 2012
Ingentaconnect.com: 10/1/12 Background Oral anticoagulants substantially reduce the risk of stroke in atrial fibrillation but are underutilised in current practice. Aim To measure the distribution of stroke risk in patients with atrial fibrillation (using the CHADS2 and CHA2DS2-VASc scores) and changes in oral anticoagulant use during 2007-2010. Design and setting Longitudinal series of cross-sectional survey in […]
Therapies
Thursday, October 11th, 2012
Content.onlinejacc.org: 10/1/12 Since the first reports of ablation therapy being used to treat atrial fibrillation, the field has exploded with studies, new techniques, and new technologies. It is no wonder that such fervor is associated with this topic. Our medical options to maintain sinus rhythm have been generally poorly effective, riddled with side effects, and […]
Therapies
Friday, October 5th, 2012
Stroke.ahajournals.org: October 2, 2012 Our goal was to compare outcomes of patients with proximal middle cerebral artery occlusions treated with intravenous tissue plasminogen activator (tPA) with those of patients treated with stent-based thrombectomy (SBT). Methods—Patients with proximal middle cerebral artery occlusions included in our prospective stroke registry were identified. Patients presenting with moderate to severe stroke […]
