The Status of Telestroke in the United States

Stroke.ahajournals.org: June 14, 2012. Little is known about adoption or success of telestroke networks outside of published or federally funded programs. Under contract to the Health Resource Services Administration, we conducted an environmental scan of telestroke programs in the United States. Methods—An analyst contacted all potential programs identified in comprehensive online searches, interviewed respondents, and collected […]

Intensive Versus Subcutaneous Insulin in Patients With Hyperacute Stroke

Stroke.ahajournals.org: June 14, 2012 Intensive insulin therapy (IIT) has not yet proven its efficacy on stroke prognosis or in the reduction of MRI infarct growth. The INSULINFARCT study aims at determining in patients with hyperacute stroke whether IIT, with a better control of poststroke hyperglycemia, would reduce subsequent MRI infarct growth than usual care with subcutaneous […]

Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia

Published: 15 May 2012. Cerebral ischemia has been shown to induce activation of matrix metalloproteinases (MMPs), particularly MMP-9, which is associated with impairment of the neurovasculature, resulting in blood-brain barrier breakdown, hemorrhage and neurodegeneration. We previously reported that the thiirane inhibitor SB-3CT, which is selective for gelatinases (MMP-2 and 9), could antagonize neuronal apoptosis after […]

Innovations in anticoagulation for stroke prevention

Medicalxpress.com: June 13, 2012. New scientific findings in anticoagulation for stroke prevention are paving the way for updates to the European Society of Cardiology (ESC) Guidelines for the management of atrial fibrillation.   Some of these findings were presented during the European Heart Rhythm Association (EHRA) sessions at Cardiostim 2012, 13-16 June, in Nice, France. Cardiostim […]

Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

Thelancet.com: June 13, 2012. Intracerebral haemorrhage accounts for about 10—15% of all strokes and is associated with high mortality and morbidity. No successful phase 3 clinical trials for this disorder have been completed. In the past 6 years, the number of preclinical and clinical studies focused on intracerebral haemorrhage has risen. Important advances have been made […]

Researchers develop method to treat strokes with white blood cell injections

Mainichi.jp:  June 12, 2012. Researchers at a hospital in Kobe have found a way to treat stroke victims using white blood cells from their bone-marrow fluid, in what could emerge as a new treatment method lessening the burden on patients. In clinical tests at the Institute of Biomedical Research and Innovation Hospital in Kobe, researchers […]

Association of Aspirin Use With Major Bleeding in Patients With and Without Diabetes

Jama.jamanetwork.com: June 6, 2012. The benefit of aspirin for the primary prevention of cardiovascular events is relatively small for individuals with and without diabetes. This benefit could easily be offset by the risk of hemorrhage. Objective  To determine the incidence of major gastrointestinal and intracranial bleeding episodes in individuals with and without diabetes taking aspirin. Design, […]

Drip-and-Ship Thrombolytic Treatment Paradigm Among Acute Ischemic Stroke Patients in the United States

Stroke.ahajournals.org:  June 5, 2012. Background and Purpose—To provide a national assessment of thrombolytic administration using drip-and-ship treatment paradigm. Methods—Patients treated with the drip-and-ship paradigm among all acute ischemic stroke patients treated with thrombolytic treatment were identified within the Nationwide Inpatient Sample. Thrombolytic utilization, patterns of referral, comparative in-hospital outcomes, and hospitalization charges related to drip-and-ship paradigm […]

Yoga Could Help Stroke Rehabilitation, Study Suggests

Huffingtonpost.com: June 3, 2012. Yoga may be a powerful tool in stroke rehabilitation, according to new research. The study, presented as two separate analyses at the annual meeting of the American College of Sports Medicine, shows that spending eight weeks in an adapted yoga program helped stroke survivors to have greater balance, be more flexible, be […]

Situationally-Sensitive Knowledge Translation and Relational Decision Making in Hyperacute Stroke: A Qualitative Study

Plosone.org: June 1, 2012. Stroke is a leading cause of disability. Early treatment of acute ischaemic stroke with rtPA reduces the risk of longer term dependency but carries an increased risk of causing immediate bleeding complications. To understand the challenges of knowledge translation and decision making about treatment with rtPA in hyperacute stroke and hence […]

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