Therapies
Saturday, June 2nd, 2012
Stroke.ahajournals.org: April 24, 2012. Background and Purpose—The aim of this study was to analyze epileptic seizures and their impact on outcome in patients with stroke treated with endovascular therapy. Methods—From December 1992 to December 2010 we managed 805 patients with stroke with endovascular therapy. Epileptic seizures, bleeding complications, and 3-month outcomes were recorded prospectively. Outcomes of […]
Therapies
Saturday, June 2nd, 2012
Stroke.ahajournals.org: April 24, 2012 Progress in Sonothrombolysis for the Treatment of Stroke In 1974, Sobbe et al1 applied 26.5-kHz ultrasound (US) to recanalize thrombosed iliofemoral arteries in dogs with minimal complications. These pioneer efforts were followed by studies showing that catheter-based or transcutaneous US can enhance the effect of fibrinolytic agents in recanalizing thrombosed arteries,2–8 thus paving the […]
Therapies
Saturday, June 2nd, 2012
Stroke.ahajournals.org: April 10, 2012. Background and Purpose—Experimental data suggest a negative interaction between x-ray contrast agents and fibrinolytic efficacy of recombinant tissue-type plasminogen activator (rtPA). We hypothesized that the application of a contrast agent before intravenous thrombolysis with rtPA reduces its clinical efficacy in acute ischemic stroke. Methods—We retrospectively studied consecutive ischemic stroke patients receiving contrast […]
Therapies
Saturday, June 2nd, 2012
Stroke.ahajournals.org: March 22, 2012 Background and Purpose—Studies suggest a protective role for statins after intracerebral hemorrhage, but many failed to assess statin discontinuation, did not include postdischarge outcomes, or did not account for withdrawal of care. We studied the relationship between preintracerebral hemorrhage statin use and in-hospital statin discontinuation on stroke severity and 30-day mortality. […]
Therapies
Saturday, June 2nd, 2012
Stroke.ahajournals.org: March 22, 2012. Background and Purpose—The publication of the European Cooperative Acute Stroke Study (ECASS III) expanded the treatment time to thrombolysis for acute ischemic stroke from 3 to 4.5 hours from symptom onset. The impact of the expanded time window on treatment rates has not been comprehensively evaluated in a population-based study. Methods—All patients […]
Therapies
Tuesday, May 29th, 2012
The Lancet, Early Online Publication, 23 May 2012. Recombinant tissue plasminogen activator (rt-PA, alteplase) improved functional outcome in patients treated soon after acute ischaemic stroke in randomised trials, but licensing is restrictive and use varies widely. The IST-3 trial adds substantial new data. We therefore assessed all the evidence from randomised trials for rt-PA in […]
Therapies
Tuesday, May 29th, 2012
Neurology.org: 5/22/2012. Objective: To determine whether statin use is associated with improved discharge disposition after ischemic stroke. Methods: We used generalized ordinal logistic regression to analyze discharge disposition among 12,689 patients with ischemic stroke over a 7-year period at 17 hospitals in an integrated care delivery system. We also analyzed treatment patterns by hospital to control for the […]
Therapies
Tuesday, May 29th, 2012
Phys.org: May 17th, 2012. A video game which improves and overcomes the physical symptoms of a stroke has been revealed. Stroke experts at Newcastle University working with new company Limbs Alive Ltd have developed the first in a planned library of action video games where the movements used to control the game are designed to enable […]
Therapies
Monday, May 21st, 2012
Nejm.org: May 17, 2012. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors’ clinical recommendations. Stage A 62-year-old woman is seen 1 week after an ischemic stroke. She had presented to […]
Therapies
Monday, May 21st, 2012
Get With the Guidelines-Stroke 2003–2010 Stroke.ahajournals.org: May 15, 2012. Background and Purpose—Secondary stroke prevention treatments vary in different regions of the US. We determined the degree to which guideline-recommended stroke treatments vary by region for patients treated at hospitals participating in a voluntary national quality improvement program, Get With The Guidelines-Stroke. Methods—Receipt of 8 guideline-recommended treatments […]
