Characterisation of the Left Atrial Neural Network and its Impact on Autonomic Modification Procedures
Atrial Fibrillation Tuesday, April 23rd, 2013CIRCEP: April 11, 2013
Background—Left atrial (LA) ganglionated plexi (GP) are part of the intrinsic cardiac autonomic nervous system and implicated in the pathogenesis of atrial fibrillation (AF). High frequency stimulation (HFS) is used to identify GP sites in humans. The effect of ablation on neural pathways connecting GPs in humans is unknown.
Methods and Results—30 patients undergoing LA ablation with autonomic modification were recruited. In patients with persistent AF, endocardial cont-HFS identified GP sites producing AV block. Read more