Complications of Catheter Ablation of Atrial Fibrillation: A Systematic Review

Atrial Fibrillation Monday, November 18th, 2013

AHA: November 15, 2013

Background—Atrial fibrillation (AF) ablation is an established therapy; however, limited data is available on associated complications. This systematic review determines the incidence and potential predictors of acute complications.

Methods and Results—Electronic searches were conducted in MEDLINE and EMBASE for English scientific literature up to the 18th June 2012. 2065-references were retrieved and evaluated for relevance. Reference lists of retrieved studies and review articles were examined to ensure all relevant studies were included. Data was extracted from 192-studies, total of 83,236-patients. The incidence of peri-procedural complications for catheter ablation of AF was 2.9% (95%CI, 2.6-3.2). There was a significant decrease in the acute complication rate in 2007-2012 compared to 2000-2006 (2.6% versus 4.0%, P=0.003). The complication rates reported were higher in prospective studies compared to those that retrospectively described complications (3.5% vs 2.7%, P= 0.03). There were no significant associations between procedure duration, ablation time, or ablation strategy, and acute complication rate. Read More

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