Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials

It remains controversial whether dual antiplatelet therapy reduces stroke more than aspirin alone.

We aimed to assess the effects of adding clopidogrel to aspirin on the occurrence of stroke and major haemorrhage in patients with vascular disease.

Meta-analysis of published randomized trials comparing the combination of clopidogrel and aspirin vs. aspirin alone that reported stroke and major bleeding.  Read more