Eligibility for Randomized Trials of Treatments Specifically for Intracerebral Hemorrhage

Clinical Trials Friday, July 26th, 2013

STROKEAHA: July 25, 2013

Background and Purpose—Acute treatments specifically for intracerebral hemorrhage (ICH) are being sought in randomized controlled trials. The treatment effect sizes in ongoing and future trials are likely to be small, necessitating large sample sizes.

Methods—We searched online trial registries for randomized controlled trials investigating an acute treatment for ICH. For the trials whose eligibility criteria could be assessed in a prospective, community-based ICH cohort study (2010–2011), we quantified the proportions of patients who were eligible and investigated influences on these proportions. Read more

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