Genetic mechanisms of atrial fibrillation: impact on response to treatment
Atrial Fibrillation Thursday, May 2nd, 2013Nature Reviews Cardiology: April 16, 2013
Atrial fibrillation (AF) is the most-common sustained arrhythmia observed in clinical practice, but response to therapy is highly variable between patients. Current drug therapies to suppress AF are incompletely and unpredictably effective and carry substantial risk of proarrhythmia and noncardiac toxicities. The limited success of therapy for AF is partially the result of heterogeneity of the underlying substrate, interindividual differences in disease mechanisms, and our inability to predict response to therapies in individual patients. Read more
