Impact of Thrombolysis on Stroke Outcome at 12 Months in a Population
Therapies Friday, March 16th, 2012Stroke.ahajournals: The Bern Stroke Project
Urs Fischer, MD, MSc; Marie-Luise Mono, MD; Marcel Zwahlen, PhD; Krassen Nedeltchev, MD; Marcel Arnold, MD; Aekatarini Galimanis, MD; Sabine Bucher, MSc; Oliver Findling, MD; Niklaus Meier, MD; Caspar Brekenfeld, MD; Jan Gralla, MD, MSc; Regula Heller, MNSc, MPH; Beatrice Tschannen, MPH; Heinz Schaad, MD; Gabriel Waldegg, MD; Thomas Zehnder, MD; Anke Ronsdorf, MD; Phillip Oswald, MD; Georg Brunner, MD; Gerhard Schroth, MD; Heinrich P. Mattle, MD for the QABE investigators
Abstract
Background and Purpose—Thrombolysis improves outcome of patients with acute ischemic stroke, but it is unknown whether thrombolysis has a measurable effect on long-term outcome in a defined population.
Methods—We prospectively assessed demographic data, management, and outcome of acute ischemic stroke patients admitted within 48 hours to 18 primary care hospitals of the canton of Bern (969 299 inhabitants) during 12 months. Blinded follow-up was obtained at 3 and 12 months. Predictors of mortality and favorable outcome (modified Rankin Scale score ≤2) at 3 and 12 months using logistic regression were analyzed. Read More
