Novel molecular targets for atrial fibrillation therapy

Nature.com: April 2, 2012. Dobromir Dobrev, Leif Carlsson & Stanley Nattel

Abstract: Atrial fibrillation is the most common type of cardiac arrhythmia, and is responsible for substantial morbidity and mortality in the general population. Current treatments have moderate efficacy and considerable risks, especially of pro-arrhythmia, highlighting the need for new therapeutic strategies. In recent years, substantial efforts have been invested in developing novel treatments that target the underlying molecular determinants of atrial fibrillation, and several new compounds are under development.  Read more

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