Physical Activity, Obesity, Weight Change and Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study

CIRCEP: June 6, 2014

ackground—Physical activity (PA) has previously been suggested to attenuate the risk of atrial fibrillation (AF) conferred by excess body weight and weight gain. We prospectively examined the relationship between body size, weight change and level of PA in a biracial cohort of middle-aged men and women.

Methods and Results—Baseline characteristics on risk factor levels were obtained on 14,219 participants from the Atherosclerosis Risk in Communities Study. AF incidence was ascertained from 1987-2009. Adjusted Cox proportional hazards models were utilized to estimate the associations between body mass index (BMI), waist circumference (WC), relative weight change, and PA level with incident AF. During follow-up, there were 1775 cases of incident AF. Read More

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