Role of Preexisting Disability in Patients Treated With Intravenous Thrombolysis for Ischemic Stroke

Therapies Wednesday, February 26th, 2014

STROKEAHA: February 4, 2014

Background and Purpose—Little is known about the effect of thrombolysis in patients with preexisting disability. Our aim was to evaluate the impact of different levels of prestroke disability on patients’ profile and outcome after intravenous thrombolysis.

Methods—We analyzed the data of all stroke patients admitted between October 2003 and December 2011 that were contributed to the Safe Implementation of Treatments in Stroke–Eastern Europe (SITS-EAST) registry. Patients with no prestroke disability at all (modified Rankin Scale [mRS] score, 0) were used as a reference in multivariable logistic regression. Read More

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