Sex Differences in Stroke Risk Among Older Patients With Recently Diagnosed Atrial Fibrillation

jama.ama-assn.org: May 9, 2012.

Context Stroke is a serious complication associated with atrial fibrillation (AF). Women with AF are at higher risk of stroke compared with men. Reasons for this higher stroke risk in women remain unclear, although some studies suggest that undertreatment with warfarin may be a cause.

Objective To compare utilization patterns of warfarin and the risk of subsequent stroke between older men and women with AF at the population level.

Design, Setting, and Patients Population-based cohort study of patients 65 years or older admitted to the hospital with recently diagnosed AF in the province of Quebec, Canada, 1998-2007, using administrative data with linkage between hospital discharge, physicians, and prescription drug claims databases. Read more

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