Statins Therapy Can Reduce the Risk of Atrial Fibrillation in Patients with Acute Coronary Syndrome: A Meta-Analysis

Atrial Fibrillation Thursday, January 17th, 2013

Int J Med Sci: 1/16/13


Background: It is a controversy whether statins therapy could be beneficial for the occurrence of atrial fibrillation (AF) in acute coronary syndrome (ACS). To clarify this problem, we performed a meta-analysis with the currently published literatures.

Methods: The electronic databases were searched to obtain relevant trials which met the inclusion criteria through October 2011. Two authors independently read the trials and extracted the related information from the included studies. Either fixed-effects models or random-effects models were assumed to calculate the overall combined risk estimates according to I2 statistic. Sensitivity analysis was conducted by omitting one study in each turn, and publication bias was evaluated using Begg’s and Egger’s test.Read More

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