Statistical Analysis of the Primary Outcome in Acute Stroke Trials
Clinical Trials Thursday, March 22nd, 2012Stroke.ahajournals.org: March 15, 2012.
Abstract
Common outcome scales in acute stroke trials are ordered categorical or pseudocontinuous in structure but most have been analyzed as binary measures. The use of fixed dichotomous analysis of ordered categorical outcomes after stroke (such as the modified Rankin Scale) is rarely the most statistically efficient approach and usually requires a larger sample size to demonstrate efficacy than other approaches. Read More
