Stroke Prevention in Patients With Atrial Fibrillation and Renal Dysfunction

Atrial Fibrillation Thursday, August 7th, 2014

STROKEAHA: June 26, 2014

The overall prevalence of atrial fibrillation (AF) is 1% of the US population. However, diagnosis of AF is increasingly common with age, and prevalence rises to ≈10% in Americans aged >80 years. As the population ages, the estimated prevalence of AF may nearly triple from 2.3 million to 5.6 million US adults by 2050, with more than half of the patients aged ≥80 years.1

The prevalence of renal dysfunction also increases with age.2 More than 10% of the US population or >20 million people aged ≥20 years have chronic kidney disease (CKD).3 The definition of CKD is glomerular filtration rate (GFR) <60 mL/min per 1.73 m2 for ≥3 months.4,5 Although both AF and CKD are more common with aging, CKD is associated with increased risk of AF independent of age. Read More

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