Successful Catheter Ablation Decreases Platelet Activation and Improves Endothelial Function in Patients with Atrial Fibrillation
Atrial Fibrillation Thursday, August 7th, 2014Heartrhythmjournal: July 25, 2014
Background
Nonvalvular atrial fibrillation (AF) confers a five-fold increased risk of stroke. Whether catheter ablation (CA) subsequently decreases prothrombotic risk is unknown.
Objective
We sought to assess the long-term effects of CA for AF on prothrombotic risk.
Methods
Fifty-seven patients undergoing CA for AF were prospectively studied. Platelet activation (CD62P [platelet P-selectin] and PAC-1 [glycoprotein IIb/IIIa] expression) and endothelial function (asymmetric dimethylarginine [ADMA] levels) were measured at baseline and 6-months post-ablation. Read more
