Susceptibility-Weighted Imaging is More Reliable Than T2*-Weighted Gradient-Recalled Echo MRI for Detecting Microbleeds
Clinical Trials Friday, September 27th, 2013AHA Stroke: August 6, 2013
Background and Purpose—We investigated the sensitivity and reliability of MRI susceptibility-weighted imaging (SWI) compared with routine MRI T2*-weighted gradient-recalled echo (GRE) for cerebral microbleed (CMB) detection.
Methods—We used data from a prospective study of cerebral amyloid angiopathy (n=9; mean age, 71±8.3) and healthy non–cerebral amyloid angiopathy controls (n=22; mean age, 68±6.3). Three raters (labeled 1, 2, and 3) independently interpreted the GRE and SWI sequences (using the phase-filtered magnitude image) blinded to clinical information. Read More