Novel molecular targets for atrial fibrillation therapy

Nature.com: April 2, 2012. Dobromir Dobrev, Leif Carlsson & Stanley Nattel Abstract: Atrial fibrillation is the most common type of cardiac arrhythmia, and is responsible for substantial morbidity and mortality in the general population. Current treatments have moderate efficacy and considerable risks, especially of pro-arrhythmia, highlighting the need for new therapeutic strategies. In recent years, substantial efforts have […]

Pharmacologic and Nonpharmacologic Therapies for Stroke Prevention in Nonvalvular Atrial Fibrillation

Onlinelibrary.wiley.com: March 27, 2012. Thromboembolism is the crucial cause of ischemic stroke in patients with atrial fibrillation (AF). Anticoagulation therapy with vitamin K antagonists, such as warfarin, have been proven to be effective for stroke prevention in AF. Nonetheless, the use of warfarin may be limited due to increased risk of bleeding, the potential interaction […]

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