Therapies
Friday, June 22nd, 2012
Stroke.ahajournals.org: June 14, 2012. Little is known about adoption or success of telestroke networks outside of published or federally funded programs. Under contract to the Health Resource Services Administration, we conducted an environmental scan of telestroke programs in the United States. Methods—An analyst contacted all potential programs identified in comprehensive online searches, interviewed respondents, and collected […]
Therapies
Friday, June 22nd, 2012
Stroke.ahajournals.org: June 14, 2012 Intensive insulin therapy (IIT) has not yet proven its efficacy on stroke prognosis or in the reduction of MRI infarct growth. The INSULINFARCT study aims at determining in patients with hyperacute stroke whether IIT, with a better control of poststroke hyperglycemia, would reduce subsequent MRI infarct growth than usual care with subcutaneous […]
Therapies
Friday, June 22nd, 2012
Published: 15 May 2012. Cerebral ischemia has been shown to induce activation of matrix metalloproteinases (MMPs), particularly MMP-9, which is associated with impairment of the neurovasculature, resulting in blood-brain barrier breakdown, hemorrhage and neurodegeneration. We previously reported that the thiirane inhibitor SB-3CT, which is selective for gelatinases (MMP-2 and 9), could antagonize neuronal apoptosis after […]
Atrial Fibrillation
Friday, June 22nd, 2012
Archneur.jamanetwork.com: Moshe Herskovitz, MD; Yitzhak Schiller, MD, PhD., Published online June 2012. Epileptic seizures are often associated with changes in cardiac autonomic function. Yet atrial fibrillation (AFib) or atrial flutter (AFlu) following epileptic seizures has only rarely been reported in the past. Objectives To describe and characterize patients who experienced lone AFib or AFlu as a consequence of epileptic […]
Atrial Fibrillation
Friday, June 22nd, 2012
Circep.ahajournals.org: June 20, 2012. Sites of high dominant frequency (DF) are thought to indicate the location of drivers of atrial fibrillation (AF) but characterisation of their spatiotemporal distribution and stability, critical to their relevance as targets for catheter ablation, requires simultaneous global mapping of the left atrium. Methods and Results—Non-contact electrograms recorded simultaneously from 256 left […]
Atrial Fibrillation
Friday, June 22nd, 2012
Newsroom.heart.org: June 20, 2012. Study Highlights: New oral blood thinners are easier to take than the older drug warfarin, but there is no clear method to reverse the action and prevent dangerous bleeding if a person suffers an accident or needs emergency surgery. In a laboratory test of reversal methods, three different approaches were able to […]
Atrial Fibrillation
Friday, June 22nd, 2012
Circep.ahajournals.org: May 1, 2012. Catheter ablation of atrial fibrillation (AF) became an effective therapy for patients with drug-refractory AF, and the indications have broadened to include nonparoxysmal AF patients. However, data about the long-term effectiveness of ablation in patients with nonparoxysmal AF are lacking. The aim of the present study was to investigate the long-term […]
Atrial Fibrillation
Friday, June 22nd, 2012
Circep.ahajournals.org: April 23, 2012. Inducibility of atrial fibrillation (AF) after pulmonary vein isolation has been used to guide additional left atrial ablation in paroxysmal AF. The sensitivity and specificity of AF induction in this setting remains uncertain. We examined the incidence and characteristics of inducible AF in patients without structural heart disease or clinical AF and […]
News
Monday, June 18th, 2012
Nejm.org June 14, 2012. BACKGROUND Although several studies have assessed the risk of venous thromboembolism with newer hormonal contraception, few have examined thrombotic stroke and myocardial infarction, and results have been conflicting. METHODS In this 15-year Danish historical cohort study, we followed nonpregnant women, 15 to 49 years old, with no history of cardiovascular disease […]
News
Monday, June 18th, 2012
Stroke.ahajournals.org: June 12, 2012. Background and Purpose—Sleep-disordered breathing (SDB) negatively impacts stroke outcome. Near-infrared spectroscopy showed the acute cerebral hemodynamic effects of SDB. Methods—Eleven patients (7 men, age 61±13 years) with acute/subacute middle cerebral artery stroke (National Institutes of Health Stroke Scale score 10±7) and SDB (apnea–hypopnea index 32±28/hour) were assessed with nocturnal polysomnography and […]
