Triple antithrombotic therapy in patients with atrial fibrillation who have undergone percutaneous coronary intervention with stent implantation

American Journal of Health-System: 9/1/12 The efficacy and safety of triple antithrombotic therapy in patients with atrial fibrillation (AF) who undergo percutaneous coronary intervention (PCI) with stent implantation are reviewed. Summary A systematic literature search of PubMed, EMBASE, and International Pharmaceutical Abstracts identified a total of 10 cohort studies and one meta-analysis investigating triple antithrombotic therapy in […]

ATVB in Focus Metabolic Syndrome and Insulin Resistance: Mechanisms and Consequences

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American Heart Association: 9/1/12. Metabolic syndrome (MetS), a clustering of risk factors for type 2 diabetes mellitus and cardiovascular disease, has been associated with cognitive dysfunction and brain abnormalities. This review describes the literature on the impact of MetS on brain and cognition and suggests directions for future research. A literature search for reports of MetS […]

Poor Long-Term Blood Pressure Control After Intracerebral Hemorrhage

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American Heart Association: August 16, 2012 Hypertension is the most important risk factor associated with intracerebral hemorrhage. We explored racial differences in blood pressure (BP) control after intracerebral hemorrhage and assessed predictors of BP control at presentation, 30 days, and 1 year in a prospective cohort study. Methods—Subjects with spontaneous intracerebral hemorrhage were identified from the […]

Simple Science @Heart: Black stroke survivors face greater risk from high blood pressure

Blog.heart.org: 8/16/12 Blacks who survive strokes caused by bleeding in the brain are more likely than whites to have high blood pressure a year later, a new study says. Continued high blood pressure increases their risk of another stroke. The study examined racial and ethnic differences in these strokes, called intracranial hemorrhage or ICH. They make up only 10 percent […]

Representation of Older Adults in the Late-Breaking Clinical Trials American Heart Association 2011 Scientific Sessions

American College of Cardiology Foundation: August 2012 Increasingly, the practice of medicine has relied on applicable and available evidence to deliver quality care. Cardiovascular medicine has led the way using numerous clinical trials as the basis of clinical practice guidelines. However, despite the strong association of aging with the development of cardiovascular disease, randomized clinical trials rarely […]

NIH launches trial to evaluate anti-inflammatory treatment for preventing heart attacks, strokes, and cardiovascular deaths

Nih.gov: 8/22/12 An international multi-site trial has launched to determine whether a common anti-inflammatory drug can reduce heart attacks, strokes, and deaths due to cardiovascular disease in people at high risk for them. This study is being supported by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health. Inflammation, […]

Accelerating the Development of New Drugs and Diagnostics: Maximizing the Impact of the Cures Acceleration Network – Workshop Summary

Advances in technologies and knowledge are creating new avenues for research and opportunities for the discovery and clinical development of innovative therapies and diagnostics. However, despite these opportunities, only a small fraction of investigational products are successfully developed into cures and therapies that can be accessed by patients. One response to the ever-widening gap between […]

After stroke, when and how to use assistive devices?

Medicalxpress.com: August 17, 2012 in Medical research With two new NIH awards, a researcher at UC’s College of Allied Health Sciences hopes to learn how augmentative and alternative communication (AAC) devices can help these patients continue to communicate. Assistant Professor of Communication Sciences and Disorders Aimee Dietz, PhD, says that for many post-stroke patients, aphasia does not completely […]

Electrophysiological and Hemodynamic Characteristics Associated With Obesity in Patients With Atrial Fibrillation

American College of Cardiology Foundation: 8/28/12 The authors sought to characterize the left atrial (LA) and pulmonary vein (PV) electrophysiological and hemodynamic features in obese patients with atrial fibrillation (AF). Background  Obesity is associated with increased risk for AF. Methods  A total of 63 consecutive patients with AF who had normal left ventricular (LV) ejection fraction and who […]

Arrhythmia and Electrophysiology

J Am Heart Assoc.: 8/17/12 Atrial fibrillation (AF) and chronic kidney disease (CKD) are prevalent in the elderly and are independently associated with increased risk of death. We evaluated risk of incident AF with advancing CKD and examined the mortality rate associated with CKD after incident AF in elderly patients. Methods and Results This retrospective cohort study […]

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