Aspirin-clopidogrel no better than aspirin alone for patients with lacunar stroke

NIH study also shows that overall stroke risk is down from 10 years ago Nih.gov: Wednesday, August 29, 2012 Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results […]

New devices successfully pluck blood clots out of the brain

By Thomas H. Maugh II Los Angeles Times August 28, 2012, 11:29 a.m.   Since tissue plasminogen activator (tPA) was approved by the Food and Drug Administration in 1996 for the dissolution of blood clots in the brain that cause strokes, it has been the primary treatment for stroke victims. But it has several limitations. In most […]

Early administration of aspirin in patients treated with alteplase for acute ischaemic stroke: a randomised controlled trial

Thelancet.com: 8/25/12 Thrombolysis with intravenous alteplase is the only approved treatment for acute ischaemic stroke. After alteplase-induced recanalisation, reocclusion occurs in 14—34% of patients, probably because of platelet activation. Early administration of antiplatelet therapy after alteplase could reduce the risk of reocclusion and improve outcome. We compared the effects of early addition of intravenous aspirin to […]

Catheter ablation for atrial fibrillation: Results from the first European registry

Medicalxpress.com: August 28, 2012 The findings were presented today at ESC Congress 2012 by Dr Elena Arbelo from Hospital Clínic de Barcelona, Spain, a co-investigator of the study. “Atrial fibrillation is the most frequent heart rhythm disorder and it represents a highly significant burden of disease and expenditure throughout the world,” explained Dr Arbelo. “The currently […]

Comparative Effectiveness of Warfarin and New Oral Anticoagulants for the Management of Atrial Fibrillation and Venous Thromboembolism: A Systematic Review

Aannals.org: August 28, 2012 New oral anticoagulants (NOACs), including direct thrombin inhibitors (DTIs) and factor Xa (FXa) inhibitors, are emerging alternatives for prophylaxis and treatment of atrial fibrillation (AF) and venous thromboembolism (VTE). Purpose: To compare the benefits and harms of NOACs versus warfarin for AF and VTE. Data Sources: MEDLINE, EMBASE, and the Cochrane Database of Systematic […]

Familial Aggregation of Lone Atrial Fibrillation in Young Persons

onlinejacc.org: 8/27/12 This study investigated whether an individual’s risk of developing lone atrial fibrillation (AF) before age 60 years is associated with lone AF in relatives. Background  Genetic factors may play a role in the development of lone AF. Methods  Using Danish national registers, a cohort was established of ∼4 million persons born between 1950 and 2008, and […]

European Society of Cardiology updates AF treatment Guidelines–Six major focus points

theheart.org: Aug 26, 2012 The treatment of atrial fibrillation is a fast-moving field. It’s a good thing, because the prevalence of the disease continues to increase. In Europe, estimates are that AF burdens almost 2% of the general population. In the past two years, enough data have come available to warrant an update to the 2010 […]

Fertile women with obesity more likely to develop atrial fibrillation

News-medical.net:  August 26, 2012 Obesity triggers atrial fibrillation in fertile women, according to research presented today at the ESC Congress 2012 by Dr Deniz Karasoy from Denmark. Atrial fibrillation and obesity are among the largest public health related challenges in the western world today. Atrial fibrillation is the commonest heart rhythm disorder and is associated with increased mortality and […]

European Society of Cardiology updates AF treatment Guidelines–Six major focus points

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Blogs.theheart.org: 8/26/12 The treatment of atrial fibrillation is a fast-moving field. It’s a good thing, because the prevalence of the disease continues to increase. In Europe, estimates are that AF burdens almost 2% of the general population. In the past two years, enough data have come available to warrant an update to the 2010 European treatment […]

Predictors of Recurrent Stroke in Patients With Symptomatic Intracranial Arterial Stenosis

Stroke.ahajournals.org: August 21, 2012 Our goal was to investigate whether initial ischemic lesion pattern can predict stroke recurrence in patients with symptomatic intracranial arterial stenosis. Methods—Of the Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis (TOSS)-2 trial participants, we included patients who underwent diffusion-weighted imaging and fluid attenuation inversion recovery imaging at baseline with a follow-up […]

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