Arterial hypertension and atrial fibrillation: Selecting antihypertensive therapy

Sciencedirect.com: 8/17/12 Arterial hypertension is the most common cardiovascular disease. Atrial fibrillation in hypertension has frequent occurrence, which increases with age. While the mechanism underlying the development of atrial fibrillation is complex, hypertension is considered one of the main pathogenic factors resulting in this arrhythmia. Hypertension is also the key risk factor for stroke, with the […]

Recent Insights into the Mechanisms Underlying Persistent Atrial Fibrillation

innovationsincrm.com: 8/1/12 Atrial fibrillation (AF) is a gradually progressive atrial disease process manifesting as the most common heart rhythm disorder. Early in its clinical course, the arrhythmia may be frequently triggered by rapid firing of impulses from focal sources. Almost all cases of true paroxysmal AF are caused by ectopic signals that originate in the thoracic […]

Global study shows brain damage from stroke can be minimised

brain

Uq.edu.au: August 13, 2012 A new study from The University of Queensland shows monitoring the brain of stroke patients using Quantitative EEG (QEEG) studies could inform treatments and therefore, minimising brain damage of stroke victims. EEG stands for electroencephalogram and is a medical test which is used to measure the electrical activity of the brain. Dr […]

Arterial Stiffness and Cerebral Small Vessel Disease The Rotterdam Scan Study

bloodcells

Stroke.ahajournals.org: August 9, 2012. Aging and vascular risk factors contribute to arterial stiffening. Increased arterial stiffness exposes the small vessels in the brain to abnormal flow pulsations and, as such, may contribute to the pathogenesis of cerebral small vessel disease. In a population-based study, we investigated the association between arterial stiffness, as measured by aortic pulse […]

Detection of Paroxysmal Atrial Fibrillation by 30-Day Event Monitoring in Cryptogenic Ischemic Stroke

Stroke.ahajournals.org: 8/7/12 Patients with cryptogenic ischemic stroke may have undetected paroxysmal atrial fibrillation (PAF). We established the Stroke and Monitoring for PAF in Real Time (SMART) Registry to determine the yield of 30-day outpatient PAF monitoring in cryptogenic ischemic stroke. Methods—The SMART Registry was a 3-year, prospective multicenter registry of 239 patients with cryptogenic ischemic stroke […]

Modeling the Association Between Particle Constituents of Air Pollution and Health Outcomes

Aje.oxfordjournals.org: 7/31/12 There is increasing interest in evaluating the association between specific fine-particle (particles with aerodynamic diameters less than 2.5 µm; PM2.5) constituents and adverse health outcomes rather than focusing solely on the impact of total PM2.5. Because PM2.5 may be related to both constituent concentration and health outcomes, constituents that are more strongly correlated with PM2.5 may […]

The risk of stroke after spinal fusion surgery: a national cohort study

Thespinejournalonline.com 6/18/12 An exposure group of 2,249 subjects who received spinal fusion surgery during the study period was compared with 2,203 control subjects matched by age, sex, and propensity score. All were followed up for 3 years for all kinds of stroke. Demographics, comorbidities, and nonmeasurable covariates were matched between the two groups. Kaplan-Meier analyses were […]

Indirect Comparisons of New Oral Anticoagulant Drugs for Efficacy and Safety When Used for Stroke Prevention in Atrial Fibrillation

Content.onlinejacc.org: 8/21/12 This study sought to perform an indirect comparison analysis of dabigatran etexilate (2 doses), rivaroxaban, and apixaban for their relative efficacy and safety against each other. Background  Data for warfarin compared against the new oral anticoagulants (OACs) in large phase III clinical trials of stroke prevention in atrial fibrillation (AF) are now available for the […]

Dose–Response Relationship of Robot-Assisted Stroke Motor Rehabilitation

Sstroke.ahajournals.org: 8/14/12. The increasing availability of robot-assisted therapy (RT), which provides quantifiable, reproducible, interactive, and intensive practice, holds promise for stroke rehabilitation, but data on its dose–response relation are scanty. This study used 2 different intensities of RT to examine the treatment effects of RT and the effect on outcomes of the severity of initial motor […]

Cardiac Resynchronization Therapy in Patients with Permanent Atrial Fibrillation: Results from the Resynchronization for Ambulatory Heart Failure Trial (RAFT)

Circheartfailure.ahajournals.org: August 14, 2012 Cardiac resynchronization (CRT) prolongs survival in patients with systolic heart failure and QRS prolongation. However; most trials excluded patients with permanent atrial fibrillation (AF). Methods and Results—The RAFT trial randomized patients to an implantable defibrillator (ICD) or ICD + CRT; stratified by the presence of permanent AF. Patients with permanent AF were […]

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