Frequency of anxiety after stroke: a systematic review and meta-analysis of observational studies

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Onlinelibrary.wiley.com: 9/27/12 Negative psychological outcomes occur frequently after stroke; however, there is uncertainty regarding the occurrence of anxiety disorders and anxiety symptoms after stroke. A systematic review of observational studies was conducted that assessed the frequency of anxiety in stroke patients using a diagnostic or screening tool. Read More

Cardiovascular disease risk in healthy children and its association with body mass index: systematic review and meta-analysis

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Bmj.com: 9/25/12 To describe the association and its magnitude between body mass index category, sex, and cardiovascular disease risk parameters in school aged children in highly developed countries. Design Systematic review and meta-analysis. Quality of included studies assessed by an adapted version of the Cochrane Collaboration’s risk of bias assessment tool. Results of included studies in […]

Blood pressure changes in acute ischemic stroke and outcome with respect to stroke etiology

Neurology.org: 9/19/12 Previous research suggested that proper blood pressure (BP) management in acute stroke may need to take into account the underlying etiology. Methods: All patients with acute ischemic stroke registered in the ASTRAL registry between 2003 and 2009 were analyzed. Unfavorable outcome was defined as modified Rankin Scale score >2. A local polynomial surface algorithm […]

Black Stroke Survivors Have Higher Blood Pressure, Increased Risk of Repeat Stroke

Explore.georgetown.edu: 8/16/12 Blacks who survived a stroke caused by bleeding in the brain had higher blood pressure than whites a year later, according to a study published today in the journal Stroke. The finding might help explain why blacks have a greater risk of suffering a second stroke than whites. The research, a part of […]

Vitamin Supplementation and Stroke Prevention

Stroke.ahajournals.org: 8/27/12 It is said that we are what we eat. It is advertised that vitamin supplements, of one kind or another, may invigorate us, our lives, and our health. Advertising has been so effective that in the year 2000, more than half of the adult population in the United States was taking dietary vitamin […]

NeuroThera® Efficacy and Safety Trial – 3 (NEST-3): a double-blind, randomized, sham-controlled, parallel group, multicenter, pivotal study to assess the safety and efficacy of transcranial laser therapy with the NeuroThera® Laser System for the treatment of acute ischemic stroke within 24 h of stroke onset

Onlinelibrary.wiley.com: 9/27/12 Transcranial laser therapy is undergoing clinical trials in patients with acute ischemic stroke. The NeuroThera® Efficacy and Safety Trial-1 was strongly positive for 90-day functional benefit with transcranial laser therapy, and post hoc analyses of the subsequent NeuroThera® Efficacy and Safety Trial-2 trial suggested a meaningful beneficial effect in patients with moderate to moderately severe […]

Clinical and Angiographic Risk Stratification and Differential Impact on Treatment Outcomes in the BARI 2D Trial

Circ.ahajournals.org: 9/26/12 The BARI 2D trial assigned patients with type 2 diabetes to prompt coronary revascularization (REV) plus intensive medical therapy versus intensive medical therapy (MED) alone and reported no significant difference in mortality. Among patients selected for CABG, REV was associated with a significant reduction in death/MI/stroke compared with MED. We hypothesized that clinical […]

Effects of Clopidogrel Added to Aspirin in Patients with Recent Lacunar Stroke

Nejm.org: 8/30/12 Lacunar infarcts are a frequent type of stroke caused mainly by cerebral small-vessel disease. The effectiveness of antiplatelet therapy for secondary prevention has not been defined. We conducted a double-blind, multicenter trial involving 3020 patients with recent symptomatic lacunar infarcts identified by magnetic resonance imaging. Patients were randomly assigned to receive 75 mg […]

Angiographic Outcomes of a Prospective Randomized Trial Comparing Endovascular Coiling of Cerebral Aneurysms With Either Cerecyte or Bare Platinum Coils

Stroke.ahajournals.org: 6/26/12 We report the primary outcome of the Cerecyte Coil Trial, a randomized trial to determine whether polymer-loaded Cerecyte coils compared with Micrus bare platinum coils improved the proportion of patients with angiographic occlusion of the aneurysm at 6 months when assessed by a core laboratory. The secondary objectives were to compare the clinical […]

Guided Antithrombotic Therapy: Current Status and Future Research Direction

Circ.ahajournals.org: 9/25/12 The National Heart, Lung, and Blood Institute (NHLBI) convened a working group to develop a research agenda to enhance the understanding and effectiveness of antithrombotic therapy. The working group brought together cardiologists, hematologists, interventionalists, clinical trialists, genetic epidemiologists, basic scientists, and other stakeholders to review coagulation, platelet activation and aggregation, and antithrombotic therapy; […]

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