Therapies
Thursday, September 27th, 2012
Stroke.ahajournals.org: 9/25/12 Pooled analyses show benefits of intravenous alteplase (recombinant tissue-type plasminogen activator) treatment for acute ischemic stroke up to 4.5 hours after onset despite marketing approval for up to 3 hours. However, the benefit from thrombolysis is critically time-dependent and if extending the time window reduces treatment urgency, this could reduce the population benefit […]
Therapies
Thursday, September 27th, 2012
Stroke.ahajournals.org: 8/23/12 Current understanding of the mechanisms underlying neural plasticity changes after stroke stems from experimental models as well as clinical studies and provides the foundation for evidence-based neurorehabilitation. In this review, we first describe the main structural and functional constituents of neural plasticity that are believed to contribute to recovery of function after stroke. […]
Therapies
Thursday, September 27th, 2012
Stroke.ahajournals.org: 8/02/12 Although stroke is a leading cause of death in the United States and around the world, many people fear this disease because of its nonfatal neurological impairments that lead to disability or dependency. Considerable research has focused on lessening the neurological effects of the acute brain injury. To date, success is limited. Despite […]
Therapies
Thursday, September 27th, 2012
Stroke.ahajournals.org: 7/24/12 Statins have been associated with increased risk of intracerebral hemorrhage (ICH), particularly in elderly patients with previous ICH. Recurrent ICH in the elderly is often related to cerebral amyloid angiopathy. Therefore, we investigated whether statin use is associated with increased prevalence and severity of microbleeds (MB), particularly cortico-subcortical microbleeds (csMB), which are frequently […]
Atrial Fibrillation
Thursday, September 27th, 2012
Circ.ahajournals.org: 9/26/12 Atrial fibrillation is common among older persons. Catheter ablation is increasingly used in patients for whom medical therapy has failed. Methods and Results—We conducted a retrospective cohort study of all fee-for-service Medicare beneficiaries 65 years or older who underwent catheter ablation for atrial fibrillation between July 1, 2007, and December 31, 2009. The […]
Atrial Fibrillation
Thursday, September 27th, 2012
Onlinelibrary.wiley.com: 9/14/12 In patients with atrial fibrillation (AF), ventricular rate control with medications has been found to be noninferior in preventing clinical events, compared to a strategy converting patients to sinus rhythm and maintaining it with medications. Guidelines have accepted rate control as an acceptable therapeutic option. Most of the prior studies excluded patients without […]
Atrial Fibrillation
Thursday, September 27th, 2012
Eurheartj.oxfordjournals.org: 9/12/12 Atrial fibrillation (AF) is the most common sustained arrhythmia. Increased body size has been associated with AF, but the relationship is not well understood. In this study, we examined the effect of increased height on the risk of AF and explore potential mediators and implications for clinical practice. Read More
Atrial Fibrillation
Thursday, September 27th, 2012
Circoutcomes.ahajournals.org: 9/4/12 Little is known regarding the adoption of direct thrombin inhibitors in clinical practice. We examine trends in oral anticoagulation for the prevention of thromboembolism in the United States. Methods and Results—We used the IMS Health National Disease and Therapeutic Index, a nationally representative audit of office-based providers, to quantify patterns of oral anticoagulant use […]
Atrial Fibrillation
Thursday, September 27th, 2012
Physiciansweekly.com: August 30, 2012 Atrial fibrillation can be bewildering for patients, especially when they’re first diagnosed. After all, their own hearts have betrayed them, beating out of rhythm, often leaving them exhausted, frustrated, and searching for answers. Increasingly, patients are finding these answers — along with treatment options and support — through social media. For […]
News
Friday, September 21st, 2012
Neurology.org: September 19, 2012 The objective of this study was to examine the joint associations of estimated glomerular filtration rate (eGFR) and urinary albumin excretion with incident stroke in a large national cohort study. Methods: Associations of urinary albumin to creatinine ratio (ACR) and eGFR with incident stroke were examined in 25,310 participants of the Reasons for […]
