Home-based stroke therapy improves outcomes, eliminates wait times, saves money

Heartandstroke.com: October 1, 2012 CALGARY – Home delivery of stroke rehabilitation improves care, eliminates waiting lists for treatment and saves hundreds of thousands of dollars annually in hospital costs, according to a quality improvement project presented today at the Canadian Stroke Congress. Early Supported Discharge, introduced as a permanent part of the Calgary Stroke Program in 2011, […]

Combined full-dose IV and endovascular thrombolysis in acute ischaemic stroke

Onlinelibrary.wiley.com: 9/27/12 There is an increasing trend to treating proximal vessel occlusions with intravenous–inter-arterial (IV-IA) thrombolysis. The best dose of IV tissue plasminogen activator (tPA) remains undetermined. We compared the combination of full-dose IV recombinant tissue plasminogen activator (rtPA) and IA thrombolytic therapy to IA therapy. Methods Between 2002 and 2009, we reviewed our computed tomographic […]

Antithrombotic treatment of atrial fibrillation: New insights

Sciencedirect.com: October 6, 2012 The incidence and prevalence of atrial fibrillation are quickly increasing, mainly due to the ageing of the population. Atrial fibrillation is, to date, a problem of public health. Atrial fibrillation is associated to a five-fold risk of stroke, which may be identified by score risks, such as CHADS2 score. The classical antithrombotic treatment […]

Alcohol consumption and the risk of incident atrial fibrillation among people with cardiovascular disease

Cmaj.ca: October 1, 2012 Moderate alcohol consumption may reduce cardiovascular events, but little is known about its effect on atrial fibrillation in people at high risk of such events. We examined the association between moderate alcohol consumption and the risk of incident atrial fibrillation among older adults with existing cardiovascular disease or diabetes. Methods: We analyzed data […]

Trends in the Incidence of Atrial Fibrillation in Older Patients Initiating Dialysis in the United States

Circ.ahajournals.org: October 2, 2012 One sixth of U.S. dialysis patients older than 65 years have been diagnosed with atrial fibrillation/flutter (AF). Little is known, however, about the incidence of AF in this population. Methods and Results—We identified 258,605 older patients (≥67 years) with fee-for-service Medicare initiating dialysis in 1995-2007, who had not been diagnosed with AF […]

Elevated Pre-Operative Serum Peptides for Collagen I and III Synthesis Result in Post-Surgical Atrial Fibrillation

This study sought to determine if serum markers for collagen I and III synthesis, the carboxyl terminal peptide from pro-collagen I (PICP) and the amino terminal peptide from pro-collagen III (PIIINP), correlate with left atrial (LA) fibrosis and post-operative atrial fibrillation (AF). Background  AF after cardiac surgery is associated with adverse outcomes. We recently demonstrated that […]

Basic Science for the Clinical Electrophysiologist

Translational Research in Atrial Fibrillation: A Quest for Mechanistically Based Diagnosis and Therapy Circep.ahajournals.org: September 27, 2012 Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice and is associated with increased risk of stroke, heart failure and death.1 However, currently available treatments for AF are less than satisfactory. Many drugs have been tried with […]

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