Science Daily: March 11, 2013 In Europe, strokes are the most common cause of physical disability among the elderly. This often result in paralysis of one side of the body, and many patients suffer much reduced physical mobility and are often unable to walk on their own. These are the hard facts the EU project […]
STROKEAHA: March 5, 2013 Background and Purpose—To investigate the relationship between severe bleeding complications and outcome after mechanical thrombectomy with or without glycoprotein-IIb/IIIa inhibitor tirofiban treatment. Methods—The study included prospectively collected data of consecutive patients with acute ischemic stroke in whom mechanical thrombectomy was perfomed in the years 2006 to 2011. Read more
Wiley: February 13, 2013 Objectives Intracranial hemorrhage (ICH) after acute stroke thrombolysis is associated with poor outcomes. Previous investigations of the relationship between preexisting antiplatelet use and the safety of intravenous (IV) thrombolysis have been limited by low event rates. The objective of this study was to determine whether preexisting antiplatelet therapy increased the risk […]
Wiley: March 12, 2013 Background Although associated with excess mortality and morbidity, obesity is associated with lower mortality after stroke. The association between obesity and risk of recurrent stroke is unclear. Aims The study aims to investigate the association in stroke patients between body mass index and risk of death and readmission for recurrent stroke. […]
Wiley: March 12, 2013 Background Multiple potential causes of stroke may coexist in ischemic stroke patients, which may affect long-term outcome. Aim We investigated whether there are differences in long-term mortality among stroke patients with coexisting potential causes. Methods We evaluated the long-term all-cause mortality and stroke or cardiovascular mortality of ischemic stroke patients with […]
Plos One: March 7, 2013 The burden of stroke is disproportionately high in the South Asian subcontinent with South Asian ethnicity conferring a greater risk of ischemic stroke than European ancestry regardless of country inhabited. While genes associated with stroke in European populations have been investigated, they remain largely unknown in South Asians. We conducted […]
STROKEAHA: March 7, 2013 Background and Purpose—Sleep-disordered breathing (SDB) represents a risk factor for cardiovascular morbidity after a cerebral ischemic event (acute ischemic event, ischemic stroke, or transient ischemic attack). In the present study, endothelial function and arterial stiffness were analyzed in patients who experienced a postacute ischemic event with relation to SDB, sleep disruption, and […]
Nature: March 1, 2013 Hypertension is a highly prevalent risk factor for stroke and dementia, and is the greatest risk factor for small-vessel disease—a frequent cause of lacunar infarction and intracerebral haemorrhage. Lacunar and cortical strokes contribute to the development of dementia in patients with, and in those without, Alzheimer disease pathology; this relationship between […]
Ann Intern Medicine: March 5, 2013 Background: Atrial fibrillation (AF) has been linked with an increased risk for cognitive impairment and dementia. Purpose: To complete a meta-analysis of studies examining the association between AF and cognitive impairment. Data Sources: Search of MEDLINE, PsycINFO, Cochrane Library, CINAHL, and EMBASE databases and hand search of article references. Study Selection: Prospective and […]
CIRCULATIONAHA: March 5, 2013 Background—Electrocardiographic QRS duration, a measure of cardiac intraventricular conduction, varies ~2-fold in individuals without cardiac disease. Slow conduction may promote reentrant arrhythmias. Methods and Results—We performed a genome-wide association study (GWAS) to identify genomic markers of QRS duration in 5,272 individuals without cardiac disease selected from electronic medical record (EMR) algorithms at […]
