Body temperature, blood infection parameters, and outcome of thrombolysis-treated ischemic stroke patients

International Journal of Stroke: April 17, 2013 Background and Aims Body temperature, inflammation, and infections may modify response to thrombolytic therapy. We studied their associations with clinical improvement after intravenous thrombolysis and three-month outcome. Methods We included 985 consecutive acute ischemic stroke patients treated with intravenous thrombolysis at the Helsinki University Central Hospital during 1995–2008. […]

Health Services and Outcomes Research

J Am Heart Assoc.:  April 15, 2013 Background It is uncertain how intracranial stenting (ICS) has been adopted nationally during a period characterized by a restrictive payment policy by the Centers for Medicare & Medicaid Services, humanitarian device exemption approval by the Food and Drug Administration, and insufficient evidence of effectiveness. We sought to determine the […]

Using Leo Plus stent as flow diverter and endoluminal remodeling in endovascular treatment of intracranial fusiform aneurysms

J NeuroIntervent Surgery: April 12, 2013 Background and purpose Treatment of intracranial fusiform aneurysms is complex and controversial, and is associated with high morbidity and mortality rates. The goal of this study was to evaluate the strategy of stent only therapy. Materials and methods A retrospective analysis of 20 patients with 20 intracranial fusiform aneurysms undergoing endovascular […]

Studies suggest physically demanding work is a risk factor for coronary heart disease

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News Medical:  April 18, 2013 Two studies presented at this year’s EuroPRevent 2013 congress suggest that demanding physical work has a detrimental effect on an individual’s risk of coronary heart disease. The first was a case-control study described by Dr Demosthenes Panagiotakos, Associate Professor of Biostatistics-Epidemiology at Harokopio University, Athens, which evaluated occupation in 250 […]

Coronary Artery Disease and Risk of Major Vascular Events After Cerebral Infarction

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STROKEAHA: April 18, 2013 Background and Purpose—The impact of asymptomatic coronary artery disease on the risk of major vascular events in patients with cerebral infarction is unknown. Methods—Four hundred five patients with acute cerebral infarction underwent carotid, femoral artery, thoracic, and abdominal aorta ultrasound examination. Of 342 patients with no known coronary heart disease, 315 underwent […]

Treatment with statins and ischemic stroke severity

Neurology: April 17, 2013 Objective: To examine the effects of pretreatment with statins at high doses (40 mg of rosuvastatin or 80 mg of any other statin) and low to moderate doses (<40 mg of rosuvastatin or <80 mg of any other statin) on ischemic stroke (IS) severity in clinical practice. Methods: Observational study of IS admissions to […]

Many Neuroscience Studies May Be Based on Bad Statistics

WIRED: April 15, 2013 The fields of psychology and cognitive neuroscience have had some rough sledding in recent years. The bumps have come from high-profile fraudsters, concerns about  findings that can’t be replicated, and criticism from within the scientific ranks about shoddy statistics. A new study adds to these woes, suggesting that a wide range of neuroscience studies lack the statistical […]

Meeting the ambition of measuring the quality of hospitals’ stroke care using routinely collected administrative data: a feasibility study

Int J Qual Health Care: April 12, 2013 Objective To examine the potential for using routinely collected administrative data to compare the quality and safety of stroke care at a hospital level, including evaluating any bias due to variations in coding practice. Design A retrospective cohort study of English hospitals’ performance against six process and outcome indicators covering […]

Predictors of Progression of Recently Diagnosed Atrial Fibrillation in REgistry on Cardiac Rhythm DisORDers Assessing the Control of Atrial Fibrillation (RecordAF)–United States Cohort

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American Journal of Cardiology: April 4, 2013 The progression of atrial fibrillation (AF) to a more sustained form is associated with increased symptoms and morbidity. The aims of the REgistry on Cardiac Rhythm DisORDers Assessing the Control of Atrial Fibrillation (RecordAF)–United States (US) cohort study were to identify the risk factors of AF progression and the […]

Atrial Fibrillation and Atrial Flutter in HIV-Infected Persons: Incidence, Risk Factors, and Association with Markers of HIV Disease Severity ONLINE FIRST

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J Am Coll Cardiology: April 1, 2013 Objectives  The purpose of this study was to investigate the associations of traditional risk factors and longitudinal measures of HIV disease severity with risk of incident atrial fibrillation (AF) in a contemporary cohort of HIV-infected individuals. Background  Cardiovascular disease is common in HIV-infected persons; however, the most common cardiac arrhythmia, […]

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