Immediate procedural outcomes in 35 consecutive pipeline embolization cases: a single-center, single-user experience

J NeuroIntervent Surgery: March 29, 2012 Background and objective Flow diverters are an exciting new class of endovascular devices that treat aneurysms by curative reconstruction of the parent artery. The Pipeline embolization device (PED) is the first FDA-approved intracranial flow diverting device available in the USA. This paper presents periprocedural results with the device in a series […]

A carving method to determine an optimal working projection using three-dimensional volume rendering digital subtraction angiography in coil embolization of cerebral aneurysms

J NeuroIntervent Surgery: February 28, 2012 Background A working projection in coil embolization of a cerebral aneurysm is usually determined using three-dimensional volume rendering digital subtraction angiography (3D VRDSA), in which the boundary between an aneurysm and its parent artery cannot be identified simultaneously on the front and back surfaces of the vessel. A new method was […]

Standard of practice: embolization of ruptured and unruptured intracranial aneurysms

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J NeuroIntervent Surgery: April 10, 2013 Since its inception, coil embolization of cerebral aneurysms was designed and approved by the US Food and Drug Administration for aneurysms considered to be high risk for microsurgical clip ligation, but it is now increasingly considered as the first line of treatment. The techniques for endovascular aneurysm treatment have […]

Relationships between brain and body temperature, clinical and imaging outcomes after ischemic stroke

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Journal of Cerebral Blood Flow & Metabolism: April 10, 2013 Pyrexia soon after stroke is associated with severe stroke and poor functional outcome. Few studies have assessed brain temperature after stroke in patients, so little is known of its associations with body temperature, stroke severity, or outcome. We measured temperatures in ischemic and normal-appearing brain […]

Transglutaminase is a therapeutic target for oxidative stress, excitotoxicity and stroke: a new epigenetic kid on the CNS block

Journal of Cerebral Blood Flow & Metabolism: April 10, 2013 Transglutaminases (TGs) are multifunctional, calcium-dependent enzymes that have been recently implicated in stroke pathophysiology. Classically, these enzymes are thought to participate in cell injury and death in chronic neurodegenerative conditions via their ability to catalyze covalent, nondegradable crosslinks between proteins or to incorporate polyamines into protein […]

Ozone is associated with cardiopulmonary and stroke emergency hospital visits in Reykjavik, Iceland 2003–2009

Environmental Health: April 8, 2013 Background Air pollution exposure is associated with hospital admissions and emergency room visits for cardiopulmonary disease and stroke. Iceland’s capital area, Reykjavik, has generally low air pollution levels, but traffic and natural sources contribute to pollution levels. The objective of this study was to investigate temporal associations between emergency hospital visits […]

Spinal ischemic stroke following dialysis: clinical and radiologic findings

Neurology: January 30, 2013 Spinal cord ischemia (SCI) is a relatively common cause of noncompressive myelopathy.1 SCI frequently involves the thoracic or lumbar cord manifesting as acute painful paraparesis but may also involve the posterior columns and autonomic fibers. Read more

Atrial Fibrillation and Atrial Flutter in HIV-Infected Persons: Incidence, Risk Factors, and Association with Markers of HIV Disease Severity

Science Direct: April 3, 2013 Objectives The purpose of this study was to investigate the associations of traditional risk factors and longitudinal measures of HIV disease severity with risk of incident atrial fibrillation (AF) in a contemporary cohort of HIV-infected individuals. Background Cardiovascular disease is common in HIV-infected persons; however, the most common cardiac arrhythmia, […]

Cost-Effectiveness of Apixaban, Dabigatran, Rivaroxaban, and Warfarin for Stroke Prevention in Atrial Fibrillation

STROKEAHA: April 2, 2013 Background and Purpose—To estimate the cost-effectiveness of stroke prevention in patients with nonvalvular atrial fibrillation by using novel oral anticoagulants apixaban 5 mg, dabigatran 150 mg, and rivaroxaban 20 mg compared with warfarin. Methods—A Markov decision-analysis model was constructed using data from clinical trials to evaluate lifetime costs and quality-adjusted life-years of […]

Management of Patients With Atrial Fibrillation

Circulation: April 1, 2013 Introduction This document is a compilation of the current American Col- lege of Cardiology Foundation/American Heart Association (ACCF/AHA) practice guideline recommendations for atrial fibrillation (AF) from the “ACC/AHA/esC 2006 Guidelines for the Management of Patients With Atrial Fibrillation),”⁎ the “2011 ACCF/AHA/Hrs Focused Update on the Management of Patients With Atrial Fibrillation […]

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