Interactions Within Stroke Systems of Care

AHA: 8/29/13 A Policy Statement From the American Heart Association/American Stroke Association In the United States and other parts of the world, various cities, states, and regions are developing multitiered systems for the care of patients with acute stroke. These systems often involve a range of healthcare components supported by various rules and regulations. The present policy statement will put […]

Mild acute ischaemic stroke—the case for thrombolytic therapy

Nature Reviews Neurology: 8/27/13 The incidence of acute ischaemic stroke with mild neurological deficits (called mild ischaemic stroke [MIS]) is increasing, and studies show that a large percentage of untreated patients have poor long-term outcomes. Many physicians do not, however, routinely treat patients with MIS with intravenous recombinant tissue plasminogen activator (rtPA)—the only thrombolytic therapy currently […]

Modelling the Efficiency of Local Versus Central Provision of Intravenous Thrombolysis After Acute Ischemic Stroke

STROKEAHA: August 27, 2013 Background and Purpose—Prehospital redirection of stroke patients to a regional center is used as a strategy to maximize the provision of intravenous thrombolysis. We developed a model to quantify the benefit of redirection away from local services that were already providing thrombolysis. Methods—A microsimulation using hospital and ambulance data from consecutive emergency […]

Intravenous thrombolysis for acute ischemic stroke occurring during hospitalization for transient ischemic attack

Wiley: 8/26/13 Background There are limited data regarding the use of intravenous thrombolysis in patients who experienced acute ischemic symptoms during their hospitalization for prior transient ischemic attack. Aim We sought to prospectively evaluate the safety and efficacy of intravenous thrombolysis for the treatment of acute ischemic stroke occurring during hospitalization for transient ischemic attack in […]

Recommendations on Angiographic Revascularization Grading Standards for Acute Ischemic Stroke

STROKEAHA: 8/6/13 Intra-arterial therapy (IAT) for acute ischemic stroke (AIS) has dramatically evolved during the past decade to include aspiration and stent-retriever devices. Recent randomized controlled trials have demonstrated the superior revascularization efficacy of stent-retrievers compared with the first-generation Merci device.1,2 Additionally, the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) 2, the Mechanical Retrieval […]

Interactions Within Stroke Systems of Care

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AHA: 8/29/13 A Policy Statement From the American Heart Association/American Stroke Association In the United States and other parts of the world, various cities, states, and regions are developing multitiered systems for the care of patients with acute stroke. These systems often involve a range of healthcare components supported by various rules and regulations. The present policy statement will put […]

Recommendations on Angiographic Revascularization Grading Standards for Acute Ischemic Stroke

STROKEAHA: 8/6/13 Intra-arterial therapy (IAT) for acute ischemic stroke (AIS) has dramatically evolved during the past decade to include aspiration and stent-retriever devices. Recent randomized controlled trials have demonstrated the superior revascularization efficacy of stent-retrievers compared with the first-generation Merci device.1,2 Additionally, the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) 2, the Mechanical Retrieval […]

Test Accuracy of Short Screening Tests for Diagnosis of Delirium or Cognitive Impairment in an Acute Stroke Unit Setting

STROKEAHA: 8/29/13 Background and Purpose—Guidelines recommend cognitive screening in acute stroke. Various instruments are available, with no consensus on a preferred tool. We aimed to describe test accuracy of brief screening tools for diagnosis of cognitive impairment and delirium in acute stroke. Methods—We collected data on sequential stroke unit admission in a single center. Four assessors […]

Quantitative Analysis of Hypoperfusion in Acute Stroke

STROKEAHA: 8/29/13 Background and Purpose—This study compares the concordance between arterial spin labeling (ASL) and dynamic susceptibility contrast (DSC) for the identification of regional hypoperfusion and diffusion-perfusion mismatch tissue classification using a quantitative method. Methods—The inclusion criteria for this retrospective study were as follows: patients with acute ischemic syndrome with symptom onset <24 hours and acquisition […]

Sex Differences in the Use of Early Do-Not-Resuscitate Orders After Intracerebral Hemorrhage

STROKEAHA: 8/27/13 Background and Purpose—Studies show that women are more likely to receive do-not-resuscitate (DNR) orders after acute medical illnesses than men. However, the sex differences in the use of DNR orders after acute intracerebral hemorrhage (ICH) have not been described. Methods—We conducted a retrospective study of consecutive patients hospitalized for acute ICH at a tertiary […]

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