News
Friday, August 30th, 2013
BMC: 8/22/13 Assistive Technologies, defined as “electrical or mechanical devices designed to help people recover movement” have demonstrated clinical benefits in upper-limb stroke rehabilitation. Stroke services are becoming community-based and more reliant on self-management approaches. Assistive technologies could become important tools within self-management, however, in practice, few people currently use assistive technologies. This study investigated […]
News
Friday, August 30th, 2013
STROKEAHA: 7/18/13 Background and Purpose—The timely detection of post-stroke depression is complicated by a decreasing length of hospital stay. Therefore, the Post-stroke Depression Prediction Scale was developed and validated. The Post-stroke Depression Prediction Scale is a clinical prediction model for the early identification of stroke patients at increased risk for post-stroke depression. Methods—The study included 410 […]
Atrial Fibrillation
Friday, August 23rd, 2013
CIRCOUTCOMES: August 6, 2013 Background—Oral anticoagulation therapy is the primary tool in reducing stroke risk in patients with nonvalvular atrial fibrillation but is underused. Patients nonpersistent with therapy contribute to this underuse. The objective of this study was to compare persistence rates in newly diagnosed nonvalvular atrial fibrillation patients treated with warfarin versus dabigatran as their […]
Atrial Fibrillation
Friday, August 23rd, 2013
BMJ Heart : 7/22/13 Background Dabigatran etexilate, a new thrombin inhibitor, has been shown to be comparable to warfarin in patients with atrial fibrillation (AF). However, there is a limited body of evidence on the efficacy and safety of using dabigatran among patients undergoing AF catheter ablation. Objective A random effects meta-analysis was performed of controlled trials comparing dabigatran and […]
Atrial Fibrillation
Friday, August 23rd, 2013
Circulation: Arrhythmia and Electrophysiology: July 19, 2013 Importance of Atrial Ischemia Background—Myocardial infarction (MI) is associated with the development of atrial fibrillation (AF). We aimed to characterize the atrial abnormalities because of MI and determine the role of ischemia to the AF substrate. Methods and Results—Forty-four sheep were studied. MI was induced by occlusion of the […]
Atrial Fibrillation
Friday, August 23rd, 2013
Heartrhythmjournal: 7/8/13 Atrial fibrillation (AF) is a leading cause of total and fatal ischemic stroke. Stroke risk after AF ablation appears to be favorably affected; however, it is largely unknown whether the benefit extends to all stroke CHADS2 risk profiles of AF patients. Read More
Atrial Fibrillation
Friday, August 23rd, 2013
Nature: 6/5/13 Atrial fibrillation (AF) is estimated to affect 2.5 million people in the United States, and results in a fivefold increase in the risk of ischemic stroke.1,2 The associated costs exceed$7 billion annually.3 Antithrombotic agents have proven benefits in preventing stroke in AF patients. Until recently, vitamin K antagonists such as warfarin were the only form […]
Clinical Trials
Friday, August 23rd, 2013
STROKEAHA: August 20, 2013 Background and Purpose—Granulocyte colony–stimulating factor (G-CSF; AX200; Filgrastim) is a stroke drug candidate with excellent preclinical evidence for efficacy. A previous phase IIa dose–escalation study suggested potential efficacy in humans. The present large phase IIb trial was powered to detect clinical efficacy in acute ischemic stroke patients.Read More
Clinical Trials
Friday, August 23rd, 2013
STROKEAHA: August 13, 2013 Background and Purpose—Surgical decompression reduces mortality and increases the probability of a favorable functional outcome after space-occupying hemispheric infarction. Its cost-effectiveness is uncertain. Methods—We assessed clinical outcomes, costs, and cost-effectiveness for the first 3 years in patients who were randomized to surgical decompression or best medical treatment within 48 hours after symptom […]
Clinical Trials
Friday, August 23rd, 2013
STROKEAHA: August 1, 2013 Background and Purpose—Mechanical thrombectomy using stent retriever devices have been advocated to increase revascularization in intracranial vessel occlusion. We present the results of a large prospective study on the use of the Solitaire Flow Restoration in patients with acute ischemic stroke. Methods—Solitaire Flow Restoration Thrombectomy for Acute Revascularization was an international, multicenter, […]
