Autonomic Denervation Added to Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation: A Randomized Clinical Trial

JACC: 8/1/13 Objectives  To investigate whether the combination of conventional pulmonary vein isolation (PVI) by circumferential antral ablation with ganglionated plexi (GP) modification in a single ablation procedure, yields higher success rates than PVI or GP ablation alone, in patients with paroxysmal atrial fibrillation (PAF). Background  Conventional PVI transects the major left atrial GP, and it is […]

Arrhythmia/Electrophysiology

STROKEAHA. July 18, 2013 Background—Atrial-based pacing is associated with lower risk of atrial fibrillation (AF) in sick sinus syndrome compared with ventricular pacing; nevertheless, the impact of site and rate of atrial pacing on progression of AF remains unclear. We evaluated whether long-term atrial pacing at the right atrial (RA) appendage versus the low RA septum […]

Ultra-Early Intravenous Stroke Thrombolysis

STROKEAHA. August 22, 2013 Do All Patients Benefit Similarly? Background and Purpose—We previously reported increased benefit and reduced mortality after ultra-early stroke thrombolysis in a single center. We now explored in a large multicenter cohort whether extra benefit of treatment within 90 minutes from symptom onset is uniform across predefined stroke severity subgroups, as compared with […]

Barriers and enablers to implementing multiple stroke guideline recommendations: a qualitative study

BMC: August 19, 2013 Translating evidence into practice is an important final step in the process of evidence-based practice. Medical record audits can be used to examine how well practice compares with published evidence, and identify evidence-practice gaps. After providing audit feedback to professionals, local barriers to practice change can be identified and targetted with […]

Recognition and management of stroke in young adults and adolescents

Neurology: 8/14/13 Approximately 15% of all ischemic strokes (IS) occur in young adults and adolescents. To date, only limited prior public health and research efforts have specifically addressed stroke in the young. Early diagnosis remains challenging because of the lack of awareness and the relative infrequency of stroke compared with stroke mimics. Moreover, the causes of […]

Advances and challenges in treatment and prevention of ischemic stroke

Wiley: 8/8/13 We review recent advances in the treatment and prevention of acute ischemic stroke, including the current state of endovascular therapy in light of five randomized controlled trials published this past year. Although no benefit of endovascular therapy over IV t-PA has been demonstrated, endovascular therapy is an appropriate treatment for acute ischemic stroke patients […]

Patient Safety in the Cardiac Operating Room: Human Factors and Teamwork

Ahajournals: 8/5/13 The cardiac surgical operating room (OR) is a complex environment in which highly trained subspecialists interact with each other using sophisticated equipment to care for patients with severe cardiac disease and significant comorbidities. Thousands of patient lives have been saved or significantly improved with the advent of modern cardiac surgery. Indeed, both mortality and morbidity for coronary artery bypass surgery […]

Barriers and enablers to implementing multiple stroke guideline recommendations: a qualitative study

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BMC: August 19, 2013 Translating evidence into practice is an important final step in the process of evidence-based practice. Medical record audits can be used to examine how well practice compares with published evidence, and identify evidence-practice gaps. After providing audit feedback to professionals, local barriers to practice change can be identified and targetted with […]

Patient Safety in the Cardiac Operating Room: Human Factors and Teamwork

Ahajournals: 8/5/13 The cardiac surgical operating room (OR) is a complex environment in which highly trained subspecialists interact with each other using sophisticated equipment to care for patients with severe cardiac disease and significant comorbidities. Thousands of patient lives have been saved or significantly improved with the advent of modern cardiac surgery. Indeed, both mortality and morbidity for coronary artery bypass surgery […]

Patient Safety in the Cardiac Operating Room: Human Factors and Teamwork

Ahajournals: 8/5/13 The cardiac surgical operating room (OR) is a complex environment in which highly trained subspecialists interact with each other using sophisticated equipment to care for patients with severe cardiac disease and significant comorbidities. Thousands of patient lives have been saved or significantly improved with the advent of modern cardiac surgery. Indeed, both mortality and morbidity for coronary artery bypass surgery […]

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