AHA Stroke: August 27, 2013 Intracerebral hemorrhage (ICH) is the deadliest stroke subtype, with 30-day mortality rates of ≈40% and significant morbidity among survivors.1 Progress has proven difficult for this disease state. Unlike ischemic stroke, where incidence seems to be declining in high-wealth countries,2and subarachnoid hemorrhage, where case fatality has improved,3 there is little evidence that ICH has […]
Neurology: August 14, 2013 Objective: We hypothesized that low rates of tissue plasminogen activator (tPA) use are only partially explained by medical considerations, and that biases, beliefs, systems, and uncertainty affect acute stroke decision-making. Methods: We generated a list of factors potentially influential in acute stroke decision-making: uncertainty, patient demographics that may predispose to bias (age, sex, comorbidities), […]
STROKEAHA: September 26, 2013 Background and Purpose—UK ambulance services assess patients with suspected stroke using the Face Arm Speech Test (FAST). The Recognition Of Stroke In the Emergency Room (ROSIER) tool has been shown superior to the FAST in identifying strokes in emergency departments but has not previously been tested in the ambulance setting. We investigated […]
JAMA: 9/25/13 Importance Three clinical decision rules were previously derived to identify patients with headache requiring investigations to rule out subarachnoid hemorrhage. Objective To assess the accuracy, reliability, acceptability, and potential refinement (ie, to improve sensitivity or specificity) of these rules in a new cohort of patients with headache. Design, Setting, and Patients Multicenter cohort study conducted at 10 […]
STROKEAHA: September 24, 2013 Background and Purpose—Previous overt stroke and subclinical stroke are frequent in patients with stroke; yet, their clinical significance and effects on stroke outcome are not clear. We studied the burden and outcome after acute ischemic stroke by prevalent ischemic brain disease in a national registry of hospitalized patients with acute stroke. Methods—Patients […]
STROKEAHA: September 10, 2013 The higher burden that many diseases pose on racial and ethnic minorities in the United States represents one of the most significant public health problems facing modern society. Stroke is no exception, with dramatic disparities in incidence and outcome among racial and ethnic minorities, rural, and disadvantaged socioeconomic groups. National Institute […]
AHA Stroke: September 5, 2013 Stroke in childhood is not common outside of congenital heart disease and a few other conditions including sickle cell disease (SCD). The background rates reported have been between 2.3 and 2.7 per 100 000 per year.1–3 Adults, on the contrary, have a background rate of ≈800 per 100 000.4 There are some […]
AHA: CIRCEP: September 18, 2013 Background—There are limited data on the predictive value of stroke risk scores for thromboembolic events (TE) after catheter ablation of atrial fibrillation (AF). Our objectives were to report the incidence of TE after AF ablation in a large contemporary AF ablation cohort. Methods and Results—Using the Leipzig Heart Center AF Ablation […]
The FinCV (Finnish CardioVersion) Study September 1, 2013 Objectives This study sought to explore the incidence and risk factors of thromboembolic complications after cardioversion of acute atrial fibrillation. Background Anticoagulation therapy is currently recommended after cardioversion of acute atrial fibrillation in patients with risk factors for stroke, but the implementation of these new consensus-based guidelines has been […]
September 1, 2013 Brief Is Not Always Safe∗ Atrial fibrillation (AF) is the most common human arrhythmia causing a significant public health burden. Restoration of sinus rhythm by cardioversion of the arrhythmia, performed either electrically or pharmacologically, has been a main therapeutic option for the treatment of AF patients during the last decades. After publication […]
