Epicardial Adipose Tissue Thickness and Ablation Outcome of Atrial Fibrillation

Plosone:   9/16/13 Epicardial fat was closely related to atrial fibrillation (AF). Transthoracic echocardiography (TTE) has been proposed to be a convenient imaging tool in assessing epicardial adipose tissue (EAT). The goal of the present study was to investigate whether the EAT thickness measured on TTE was a useful parameter in predicting procedural outcomes of AF […]

Atherosclerosis/Lipoproteins: Carotid Atherosclerosis and Incident Atrial Fibrillation

ATVBAHA: September 12, 2013 Objective—Atrial fibrillation (AF) and atherosclerotic vascular disease are closely entangled disorders and often coexist. Whether atherosclerosis predisposes to the development of AF has not been fully elucidated. Approach and Results—This study was performed within the framework of the Bruneck Study, a population-based survey with near-complete participation (932 of 1000), long-term follow-up […]

New StopAfib.org Video Explains the Hidden Afib Risks for Atrial Fibrillation Awareness Month

September 12, 2013 September Is Atrial Fibrillation Awareness Month: StopAfib.org Video Explains the Hidden Afib Risks Dallas, TX, September 11, 2013 — Atrial fibrillation (also called afib or AF) is an irregular heartbeat (or heart rhythm) and is a much more serious condition than many patients – and their family members – realize. Many patients […]

Educational Intervention Improves Anticoagulation Control in Atrial Fibrillation Patients: The TREAT Randomised Trial

PLOSONE: 9/9/13 Stroke prevention in atrial fibrillation (AF), most commonly with warfarin, requires maintenance of a narrow therapeutic target (INR 2.0 to 3.0) and is often poorly controlled in practice. Poor patient-understanding surrounding AF and its treatment may contribute to the patient’s willingness to adhere to recommendations. Method A theory-driven intervention, developed using patient interviews and […]

Stroke Propensity Is Increased under Atrial Fibrillation Hemodynamics: A Simulation Study

PLOS: 9/5/13 Atrial fibrillation (AF) is the most common sustained dysfunction in heart rhythm clinically and has been identified as an independent risk factor for stroke through formation and embolization of thrombi. AF is associated with reduced cardiac output and short and irregular cardiac cycle length. Although the effect of AF on cardiac hemodynamic parameters […]

Early Dual versus Mono Antiplatelet Therapy for Acute Non-Cardioembolic Ischemic Stroke or Transient Ischemic Attack: An Updated Systematic Review and Meta-Analysis

CIRCULATIONAHA: September 12, 2013 Background—Emerging studies suggest that early administration of dual antiplatelet therapy may be better than monotherapy for prevention of early recurrent stroke and cardiovascular outcomes in acute ischemic stroke (IS) and transient ischemic attack (TIA). We performed a meta-analysis of randomized controlled trials (RCTs) evaluating dual versus mono antiplatelet therapy for acute non-cardioembolic […]

Electromechanical-Assisted Training for Walking After Stroke: Updated Evidence

AHA: 9/12/13 Improving walking after stroke is one of the main goals of rehabilitation. Electromechanical-assisted gait training uses specialist machines to assist walking practice and might help to improve walking after stroke. Objectives: Our systematic review examined the effects of electromechanical and robotic-assisted gait training devices for improving walking after stroke and also assessed the acceptability and safety of this type of therapy. Read […]

Colony-Stimulating Factors for the Treatment of Stroke

AHA: 9/12/13 Colony-stimulating factors (CSFs) regulate bone marrow production of red cells, white cells, and platelets. CSFs have been hown to be neuroprotective in experimental stroke, and some SFs also mobilize bone marrow stem cells into the circulation. We systematically reviewed the safety and efficacy of CSFs in people with acute or subacute stroke and their effect on circulating blood counts.1 Read more

Intracluster correlation coefficients and reliability of randomized multicenter stroke trials within VISTA

Wiley: 9/5/13 Reliable estimates of intracluster correlation coefficients (ICCs) for specific outcome measures are crucial for sample size calculations of future cluster randomized trials. ICCs indicate the proportion of data variability that is explained by defined levels of clustering. Aims In this manuscript, we present potentially valuable and reliable estimates of ICCs for specific baseline and […]

Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence

Diabetes Care: August 13, 2013 OBJECTIVE Transcription factor 7-like 2 (TCF7L2) polymorphisms are strongly associated with type 2 diabetes, but controversially with plasma lipids and cardiovascular disease. Interactions of the Mediterranean diet (MedDiet) on these associations are unknown. We investigated whether the TCF7L2-rs7903146 (C>T) polymorphism associations with type 2 diabetes, glucose, lipids, and cardiovascular disease incidence were modulated […]

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