Neurology: October 9, 2013 Objective: To evaluate the 5-year impact of stroke and TIA on utility and quality-adjusted survival. Methods: TIA and stroke patients from a UK population-based study (Oxford Vascular Study) were recruited from 2002 to 2007, and followed up until 2012. Quality of life was assessed over 5 years using the EQ-5D (EuroQol-5 Dimensions), with responses […]
Neurology: October 9, 2013 Implication of basal ganglia Objective: To examine the relationship between reward sensitivity and self-reported apathy in stroke patients and to investigate the neuroanatomical correlates of both reward sensitivity and apathy. Methods: In this prospective study, 55 chronic stroke patients were administered a questionnaire to assess apathy and a laboratory task to examine reward sensitivity […]
STROKEAHA: October 8, 2013 Background and Purpose—Organized stroke systems of care include Primary Stroke Center (PSC) certification and preferential emergency medical services (EMS) routing of suspected patients with stroke to designated PSCs. Stroke EMS routing is not nationally governed; in California, routing is determined by county. EMS routing policies might provide an incentive for PSC accreditation. […]
STROKEAHA: October 8, 2013 Implications for Intra-arterial Therapy Background and Purpose—Thin-section noncontrast computed tomography images can be used to measure hyperdense clot length in acute ischemic stroke. Clots ≥8 mm have a very low probability of intravenous tissue-type plasminogen activator recanalization and hence may benefit from a bridging intra-arterial approach. To understand the prevalence of […]
STROKEAHA: October 3, 2013 Background and Purpose—The extent of diffusion lesion on pretreatment imaging is a risk factor for poor outcome and hemorrhagic transformation after thrombolysis, and volumes of 70 to 100 mL have been advocated as cut-offs. However, estimating diffusion-weighted imaging (DWI) lesion volume (VolDWI) in the acute setting may be cumbersome. We aimed to […]
Springer: October 2, 2013 For more than 5 decades, the only available treatment for the prevention of atrial fibrillation (AF)-related stroke were the vitamin K antagonists. Recently, novel oral anticoagulants (NOAC) have been approved for the prevention of AF-related stroke. In the present article, the cost effectiveness of AF-related stroke-prevention strategies is reviewed. The emphasis on […]
CIRCULATIONAHA: 10/1/13 Atrial fibrillation (AF) is the most common human arrhythmia in the world and, depending on individual demographics, afflicts from 0.1% to 4% of the general population.1 With the steady rise of cardiovascular disease in the industrialized world, it is no surprise that the incidence of AF is also increasing.2,3 However, despite its ubiquitous presence in […]
Europace: 10/1/13 The purpose of this European Heart Rhythm Association (EHRA) survey was to assess clinical practice in relation to stroke prevention in atrial fibrillation (AF), particularly into the use of novel oral anticoagulants (NOACs) for stroke prevention, among members of the EHRA electrophysiology (EP) research network. In this EP Wire survey, we have provided some […]
J Gerontol A Biol Sci Med Sci: September 28, 2013 Background. Atrial fibrillation (AF) is associated with higher risk of dementia and Alzheimer’s disease. To better understand the mechanism, we examined neuropathologic changes seen with AF. Methods. We analyzed data from an autopsy series arising from a population-based, prospective cohort study set within Group Health, an integrated health […]
Heart Rhythm Journal: 5/22/13 Background Many patients who develop atrial fibrillation (AF) will experience a worsening of their arrhythmia over time. The optimal time to proceed with catheter ablation during the disease course is unknown. Further, whether delays in treatment will negatively influence outcomes is unknown. Objective The purpose of this study was to examine the […]
