Therapies
Friday, November 22nd, 2013
Wiley: 11/21/13 The currently proven time window for thrombolysis in ischemic stroke is 4·5 h. Beyond this, the risks and benefits of thrombolysis are uncertain. Aims To determine whether thrombolysis and reperfusion were beneficial after 4·5 h, we examined clinical and radiological outcomes in patients treated with tissue plasminogen activator or placebo within 4·5–6 h, using data from the […]
Therapies
Friday, November 22nd, 2013
STROKEAHA: November 21, 2013 Results From Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register Background and Purpose—Temporal variations of thrombolysis delivery and their influence on outcome have been reported with controversial results. In this large cohort study, we evaluated whether thrombolytic treatment has a within-day and weekly variability corresponding to circadian and weekly patterns of […]
Therapies
Friday, November 22nd, 2013
STROKEAHA: November 19, 2013 Background and Purpose—Analysis of quality of care for in-hospital stroke has not been previously performed at the national level. This study compares patient characteristics, process measures of quality, and outcomes for in-hospital strokes with those for community-onset strokes in a national cohort. Methods—We performed a retrospective cohort study of the Get With […]
Therapies
Friday, November 22nd, 2013
PLOS: Nov 18, 2013 Various studies demonstrate better patient outcome and higher thrombolysis rates achieved by centralized stroke care compared to decentralized care, i.e. community hospitals. It remains largely unclear how to improve thrombolysis rate in decentralized care. The aim of this simulation study was to assess the impact of previously identified success factors in […]
Therapies
Friday, November 22nd, 2013
Nature Reviews Neurology: 11/12/13 Following stroke, patients are commonly left with debilitating motor and speech impairments. This article reviews the state of the art in neurological repair for stroke and proposes a new model for the future. We suggest that stroke treatment—from the time of the ictus itself to living with the consequences—must be fundamentally neurological, […]
News
Friday, November 22nd, 2013
STROKEAHA: November 21, 2013 Background and Purpose—Ischemic stroke (IS) and coronary artery disease (CAD) share several risk factors and each has a substantial heritability. We conducted a genome-wide analysis to evaluate the extent of shared genetic determination of the two diseases. Methods—Genome-wide association data were obtained from the METASTROKE, Coronary Artery Disease Genome-wide Replication and Meta-analysis […]
News
Friday, November 22nd, 2013
STROKEAHA: November 21, 2013 Background and Purpose—The occurrence of a transient ischemic attack (TIA) increases an individual’s risk for subsequent stroke. The objectives of this study were to determine clinical features of patients with TIA associated with impending (≤7 days) stroke and to develop a clinical prediction score for impending stroke. Methods—We conducted a prospective cohort […]
News
Friday, November 22nd, 2013
Wiley: 11/21/13 Background and Aims Providing evidence-based clinical care reduces disability and mortality rates following stroke. We examined if compliance with evidence-based processes of care were different for patients with intracerebral haemorrhage when compared with ischemic stroke and sought to describe differences in health outcomes during hospitalization and at time of discharge for these stroke subtypes. […]
News
Friday, November 22nd, 2013
STROKEAHA: November 19, 2013 Background and Purpose—Geographically distinct multidisciplinary stroke care units (SCUs) have been shown by systematic reviews to have superior patient outcomes compared with conventional care in general medical wards. However, the effectiveness of SCUs in smaller North American community hospitals is less well defined. The objective of this study was to determine […]
News
Friday, November 22nd, 2013
Cambridge University Press: 11/15/13 The prevalence and determinates of depression in 67 older adults were assessed at 1 year post-stroke. The sample had an average age of 74 years (SD = 7, range = 60–87 years) at the time of their stroke and 52% were female. The relative contribution of demographic (gender, age), medical (history of previous […]
