2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults

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AHA: 11/12/13 Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk  The goals of the American College of Cardiology (ACC) and the American Heart Association (AHA) are to prevent cardiovascular (CV) diseases, improve the management of people who have these diseases through professional education and research, and develop guidelines, standards and policies that promote optimal […]

A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

AHA: 11/12/13   Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk  The goals of the American College of Cardiology (ACC) and the American Heart Association (AHA) are to prevent cardiovascular (CV) diseases, improve the management of people who have these diseases through professional education and research, and develop guidelines, standards and policies that promote […]

A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

AHA: 11/12/13 Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk  The goals of the American College of Cardiology (ACC) and the American Heart Association (AHA) are to prevent cardiovascular (CV) diseases, improve the management of people who have these diseases through professional education and research, and develop guidelines, standards and policies that promote […]

Prevalence of Silent Cerebral Ischemia in Paroxysmal and Persistent Atrial Fibrillation and Correlation With Cognitive Function

JACC: 11/19/13 Objectives  The aim of this study was to compare the prevalence of silent cerebral ischemia (SCI) and cognitive performance in patients with paroxysmal and persistent atrial fibrillation (AF) and controls in sinus rhythm. Background  Large registries have reported a similar risk for symptomatic stroke in both paroxysmal and persistent AF. The relationship among paroxysmal and persistent AF, […]

Complications of Catheter Ablation of Atrial Fibrillation: A Systematic Review

AHA: November 15, 2013 Background—Atrial fibrillation (AF) ablation is an established therapy; however, limited data is available on associated complications. This systematic review determines the incidence and potential predictors of acute complications. Methods and Results—Electronic searches were conducted in MEDLINE and EMBASE for English scientific literature up to the 18th June 2012. 2065-references were retrieved and […]

High Sensitivity Troponin I for Risk Assessment in Patients with Atrial Fibrillation: Insights from the ARISTOTLE Trial

CIRCULATIONAHA: November 13, 2013 Background—High sensitivity troponin-I (hs-TnI) measurements improves risk assessment for cardiovascular events in many clinical settings, the added value in atrial fibrillation (AF) patients has not been described. Methods and Results—At randomization hs-TnI was analyzed in 14,821 AF patients in the ARISTOTLE trial comparing apixaban with warfarin. The associations between hs-TnI concentrations and […]

Cost-Effectiveness of Oral Anticoagulants for Treatment of Atrial Fibrillation

CIRCOUTCOMES: November 12, 2013 Background—New anticoagulants may improve health outcomes in patients with atrial fibrillation, but it is unclear whether their use is cost-effective. Methods and Results—A Markov state transition was created to compare 4 therapies: dabigatran 150 mg BID, apixaban 5 mg BID, rivaroxaban 20 mg QD, and warfarin therapy. The population included those with […]

Orthostatic Change in Blood Pressure and Incidence of Atrial Fibrillation: Results from a Bi-Ethnic Population Based Study

PLOS: 11/11/13 Autonomic fluctuations are associated with the initiation and possibly maintenance of atrial fibrillation (AF). However, little is known about the relationship between orthostatic blood pressure change, a common manifestation of autonomic dysfunction, and incident AF. Methods We examined whether supine-to-standing changes in systolic blood pressure (SBP) are associated with incident AF in 12,071 African […]

Effects of Immediate Blood Pressure Reduction on Death and Major Disability in Patients With Acute Ischemic Stroke The CATIS Randomized Clinical Trial

JAMA: 11/17/13 Importance  Although the benefit of reducing blood pressure for primary and secondary prevention of stroke has been established, the effect of antihypertensive treatment in patients with acute ischemic stroke is uncertain. Objective  To evaluate whether immediate blood pressure reduction in patients with acute ischemic stroke would reduce death and major disability at 14 days or hospital […]

Factor Xa Inhibitors Versus Vitamin K Antagonists for Preventing Cerebral or Systemic Embolism in Patients With Atrial Fibrillation

ASA: 11/12/13 Atrial fibrillation (AF) is the most common type of arrhythmia in adults and becomes more common with increased age. Management of people with AF aims at preventing thromboembolic complications, and anticoagulant treatment with vitamin K antagonists (VKAs) has been the therapy of choice for many decades. A new class of anticoagulants, the factor Xa […]

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