Therapies
Saturday, December 14th, 2013
J NeuroIntervent Surg: 9/7/13 Abstract Purpose To evaluate the clinical outcome and MRI findings after carotid artery stenting (CAS) without post-dilatation. Methods Between May 2005 and April 2012, a total of 169 consecutive patients (61.4% symptomatic) underwent 176 CAS procedures performed with an embolic protection device (GuardWire, n=116; FilterWire EZ, n=60). All stents were deployed without post-dilatation. Periprocedural […]
News
Saturday, December 14th, 2013
STROKEAHA: December 12, 2013 Background and Purpose—Several risk scores have been developed to predict the stroke risk after transient ischemic attack (TIA). However, the validation of these scores in different cohorts is still limited. The objective of this study was to elucidate whether these scores were able to predict short-term and long-term risks of stroke in […]
News
Saturday, December 14th, 2013
CIRCOUTCOMES: December 10, 2013 Background—The prevalence of severe obesity is rising in the United States. Although mild to moderately elevated body mass index (BMI) is associated with reduced mortality after acute ischemic stroke, less is known about severe obesity. Methods and Results—Patients with acute ischemic stroke (n=1791) ≥45 years were identified from the biethnic population–based Brain […]
News
Saturday, December 14th, 2013
STROKEAHA: December 12, 2013 Background and Purpose—Because robotic devices record the kinematics and kinetics of human movements with high resolution, we hypothesized that robotic measures collected longitudinally in patients after stroke would bear a significant relationship to standard clinical outcome measures and, therefore, might provide superior biomarkers. Methods—In patients with moderate-to-severe acute ischemic stroke, we used […]
News
Saturday, December 14th, 2013
STROKEAHA: December 12, 2013 Background and Purpose—The Interventional Management of Stroke (IMS)-III trial randomized patients with acute ischemic stroke to intravenous tissue-type plasminogen activator (tPA) plus endovascular therapy versus intravenous tPA therapy alone within 3 hours from symptom onset. A predefined secondary hypothesis was that subjects with significant early ischemic change on the baseline scan would […]
News
Saturday, December 14th, 2013
Nature Reviews Neurology: 10 December 2013 Subarachnoid haemorrhage (SAH) causes early brain injury (EBI) that is mediated by effects of transient cerebral ischaemia during bleeding plus effects of the subarachnoid blood. Secondary effects of SAH include increased intracranial pressure, destruction of brain tissue by intracerebral haemorrhage, brain shift, and herniation, all of which contribute to pathology. […]
Atrial Fibrillation
Saturday, December 14th, 2013
Ann Intern Med: 12/3/13 Background: Atrial fibrillation (AF) prediction models have unclear clinical utility given the absence of AF prevention therapies and the immutability of many risk factors. Premature atrial contractions (PACs) play a critical role in AF pathogenesis and may be modifiable. Objective: To investigate whether PAC count improves model performance for AF risk. Design: Prospective cohort […]
Atrial Fibrillation
Saturday, December 14th, 2013
Everyday Health: 11/27/13 If traditional treatments aren’t enough to control your symptoms living with atrial fibrillation, afib, and it means you’re not living the way you’d like, a clinical trial may provide the answer you need. “Patients are looking for highly experienced doctors, and most of those are very engaged in doing clinical trials. The clinical […]
Atrial Fibrillation
Saturday, December 14th, 2013
STROKEAHA: November 26, 2013 Background and Purpose—Preadmission oral anticoagulant treatment (OAT) has been linked with less severe stroke and a better outcome in patients with atrial fibrillation. However, the existing studies have methodological limitations and have, with one exception, not included hemorrhagic strokes. We performed a nationwide historic follow-up study using data from population-based healthcare registries […]
Atrial Fibrillation
Saturday, December 14th, 2013
Eur Heart J: November 25, 2013 Aims Atrial fibrillation increases the risks of stroke, heart failure, and death, and anticoagulation therapy increases the risk of gastrointestinal haemorrhage. However, the relative event rates for these outcomes are not well described. We sought to define the risks of major clinical events in older adults after a new diagnosis of […]
