Guidance for updating clinical practice guidelines: a systematic review of methodological handbooks

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Implementationscience: January 2, 2014 Background Updating clinical practice guidelines (CPGs) is a crucial process for maintaining the validity of recommendations. Methodological handbooks should provide guidance on both developing and updating CPGs. However, little is known about the updating guidance provided by these handbooks. Methods We conducted a systematic review to identify and describe the updating guidance […]

An update on Italian Stroke Organization guidelines on carotid endarterectomy and stenting

Wiley: DEC 22, 2013 One hundred and fifty-three authors, 45 Italian scientific societies, and two Italian patients’ associations participated in drafting the Italian Stroke Organization document, which has become the national guideline for the prevention and treatment of stroke in Italy. For the surgical therapy section of the Italian Stroke Organization document, the main trials on […]

2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)

JAMA: December 18, 2013 Hypertension is the most common condition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if not detected early and treated appropriately. Patients want to be assured that blood pressure (BP) treatment will reduce their disease burden, while clinicians want guidance on hypertension management using the best scientific […]

AACE Rejects Heart Groups’ Guidelines

Medpagetoday: Dec 16, 2013 The American Association of Clinical Endocrinologists said it doesn’t endorse the latest lipid and obesity guidelines from the American Heart Association and the American College of Cardiology, recommending instead that its members refer to the society’s own guidance in these areas. In a letter to its members, AACE questioned the scientific basis […]

Guideline clinical nutrition in patients with stroke

Etsmjournal: 12/1/14 Stroke is regularly accompanied by dysphagia and other factors associated with decreased nutritional intake. Dysphagia with aspiration pneumonia and insufficient nutritional intake lead to worse outcome after stroke. This guideline is the first chapter of the guideline “Clinical Nutrition in Neurology” of the German Society for Clinical Nutrition (DGEM) which itself is one […]

Initiation of warfarin in patients with atrial fibrillation: early effects on ischaemic strokes

Eur Heart J: December 18, 2013 Aims An increased risk of stroke was observed in two atrial fibrillation (AF) trials of oral factor Xa inhibitors, when patients were transitioned to open label warfarin at the end of the study. The objective of this study is to determine whether initiation of warfarin is associated with an increased risk […]

Antihypertensive treatment and risk of atrial fibrillation: a nationwide study

Eur Heart J: December 17, 2013 Aims To examine the associations between antihypertensive treatment with angiotensin-converting enzyme inhibitors (ACEis) or angiotensin receptor blockers (ARBs), β-blockers, diuretics, or calcium-antagonists, and risk of atrial fibrillation. We examined these associations using the entire Danish population from 1995 through 2010. Methods and results Excluding medication used in atrial fibrillation, we matched individuals […]

Worldwide Epidemiology of Atrial Fibrillation: A Global Burden of Disease 2010 Study

CIRCULATIONAHA: December 17, 2013 Background—The global burden of atrial fibrillation (AF) is unknown. Methods and Results—We systematically reviewed population-based studies of AF published 1980-2010, from the 21 Global Burden of Disease (GBD) regions to estimate global/regional prevalence, incidence, as well as morbidity and mortality related to AF (DisModMR software). Of 377 potential studies identified, 184 met […]

Avoiding permanent atrial fibrillation: treatment approaches to prevent disease progression

Dovepress: December 16, 2013 Abstract: Atrial fibrillation (AF) is the most common sustained arrhythmia and a major global public health problem due to its associated morbidity, including stroke and heart failure, diminished quality of life, and increased mortality. AF often presents initially in a paroxysmal form and may progress to a more sustained form over time. Evidence […]

Clinical course of atrial fibrillation in older adults: the importance of cardiovascular events beyond stroke

Eur Heart J: November 25, 2013 Aims Atrial fibrillation increases the risks of stroke, heart failure, and death, and anticoagulation therapy increases the risk of gastrointestinal haemorrhage. However, the relative event rates for these outcomes are not well described. We sought to define the risks of major clinical events in older adults after a new diagnosis of […]

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