Clinical Trials
Thursday, January 9th, 2014
Wiley: JAN 3, 2014 Background The most effective and efficient model for providing organized stroke care remains uncertain. This study aimed to compare the effect of two models in a randomized controlled trial. Methods Patients with acute stroke were randomized on day one of admission to combined, co-located acute/rehabilitation stroke care or traditionally separated acute/rehabilitation stroke […]
Clinical Trials
Thursday, January 9th, 2014
Neurology: January 2, 2014 Objective: To assess whether adding clopidogrel to acetylsalicylic acid (ASA) has a long-term protective vascular effect in patients with lacunar stroke while taking ASA. Methods: Post hoc analysis of 838 patients with ASA failure and recent lacunar stroke from the Secondary Prevention of Small Subcortical Strokes Trial (SPS3) cohort randomly allocated to aspirin (325 […]
Clinical Trials
Thursday, January 9th, 2014
CIRCEP: January 1, 2014 Background—Restoring sinus rhythm in patients with heart failure (HF) and atrial fibrillation (AF) may improve left ventricular (LV) function and HF symptoms. We sought to compare the impact of a catheter ablation strategy with that of a medical rate control strategy in patients with persistent AF and HF. Methods and Results—Patients with […]
Clinical Trials
Thursday, January 9th, 2014
JACC: December 2013 Objectives – To report additional safety results from the Rivaroxaban Once-daily oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF). Background ROCKET AF demonstrated similar risks of stroke/systemic embolism and major/nonmajor clinically relevant bleeding (principal safety endpoint) with rivaroxaban and warfarin. […]
Clinical Trials
Thursday, January 9th, 2014
CIRCULATIONAHA: November 25, 2013 Background—Radiofrequency ablation of atrial fibrillation has been associated with some risk of thromboembolic events. Previous studies showed that preventive short episodes of forearm ischemia (remote ischemic preconditioning [IPC]) reduce exercise-induced platelet reactivity. In this study, we assessed whether remote IPC has any effect on platelet activation induced by radiofrequency ablation of atrial […]
Therapies
Thursday, January 9th, 2014
J NeuroIntervent Surg: January 2, 2014 While intravenous administration of tissue plasminogen activator (tPA) remains the only FDA-approved treatment modality for acute ischemic stroke, many patients do not meet the criteria for intravenous tPA and are offered intra-arterial therapy. Rapid advances in devices and approaches have marked the evolution of thrombectomy over the past decade from […]
Therapies
Thursday, January 9th, 2014
STROKEAHA: January 2, 2014 Background and Purpose—Thrombolysis in acute stroke is effective up to 4.5 hours after symptom onset but relies on early recognition, prompt arrival in hospital, and timely brain scanning. This study aimed to establish the cost-effectiveness of increasing thrombolysis rates through a series of hypothetical change strategies designed to optimize the acute care […]
Therapies
Thursday, January 9th, 2014
Wiley: 12/23/13 Background Treatment rates with intravenous tissue plasminogen activator vary by region, which can be partially explained by organizational models of stroke care. A recent study demonstrated that prehospital factors determine a higher thrombolysis rate in a centralized vs. decentralized model in the north of the Netherlands. Aim To investigate prehospital factors that may explain […]
Therapies
Thursday, January 9th, 2014
Etsmjournal: 12/1/14 Stroke is regularly accompanied by dysphagia and other factors associated with decreased nutritional intake. Dysphagia with aspiration pneumonia and insufficient nutritional intake lead to worse outcome after stroke. This guideline is the first chapter of the guideline “Clinical Nutrition in Neurology” of the German Society for Clinical Nutrition (DGEM) which itself is one part […]
News
Thursday, January 9th, 2014
Neurology: 1/2/14 Objectives: Stroke and TIA are recognized complications of acute herpes zoster (HZ). In this study, we evaluated HZ as a risk factor for cerebrovascular disease (stroke and TIA) and myocardial infarction (MI) in a UK population cohort. Methods: A retrospective cohort of 106,601 HZ cases and 213,202 controls matched for age, sex, and general practice […]
