Therapies
Wednesday, October 5th, 2016
Neurology, 14 Septemberߠ Objective: To determine patient and hospital characteristics associated with not providing IV tissue plasminogen activator (tPA) to eligible patients with acute ischemic stroke (AIS) in clinical practice. … Conclusions: Overall, about one-quarter of eligible patients with AIS presenting within 2 hours of stroke onset failed to receive tPA treatment. Thrombolysis has improved dramatically over […]
Therapies
Wednesday, October 5th, 2016
Stroke, 23 August 2016 Background and Purpose—Sex-specific disparities in stroke care including thrombolytic therapy and early hospital admission are reported. In a large registry of Florida and Puerto Rico hospitals participating in the Get With The Guidelines—Stroke program, we sought to determine sex-specific differences in ischemic stroke performance metrics and overall thrombolytic treatment. :… Conclusions—Women received comparable stroke […]
Therapies
Wednesday, October 5th, 2016
Stroke, 1 August 2016 Background and Purpose—Understanding physician decision making is increasingly recognized as an important topic of study, especially in stroke care. We sought to characterize the process of acute stroke decision making among neurologists in the United States and Canada from clinical and epistemological perspectives. … Conclusions—Diagnostic certainty and likelihood of treatment with tissue-type plasminogen activator […]
Therapies
Wednesday, October 5th, 2016
Implement Sci, 8 April 2016 Background Thrombolysis using intravenous (IV) tissue plasminogen activator (tPA) is one of few evidence-based acute stroke treatments, yet achieving high rates of IV tPA delivery has been problematic. The 4.5-h treatment window, the complexity of determining eligibility criteria and the availability of expertise and required resources may impact on treatment rates, with […]
Therapies
Wednesday, October 5th, 2016
Stroke, 14 October 2015 Background Primary stroke centers (PSCs) utilize more recombinant tissue plasminogen activator (rt-PA) than non-PSCs. The impact of PSCs on racial disparities in rt-PA use is unknown. … Conclusions Racial disparities in intravenous rt-PA use were not reduced by presentation to PSCs. Black patients were less likely to receive thrombolytic treatment than white patients at […]
Clinical Trials
Wednesday, October 5th, 2016
Stroke, 1 October 2015 Background and Purpose—Emergency medical services routing of patients with acute stroke to designated centers may increase the proportion of patients receiving care at facilities meeting national standards and augment recruitment for prehospital stroke research. … Conclusions—The establishment of a regionalized emergency medical services system of acute stroke care dramatically increased the proportion of patients […]
Clinical Trials
Wednesday, October 5th, 2016
JAMA Neurol, February 2016 Importance Intra-arterial treatment (IAT) for acute ischemic stroke caused by intracranial arterial occlusion leads to improved functional outcome in patients treated within 6 hours after onset. The influence of treatment delay on treatment effect is not yet known. Objective To evaluate the influence of time from stroke onset to the start of […]
Clinical Trials
Wednesday, October 5th, 2016
Trials, 18 December 2015 Background Effective recruitment is an essential element of successful research but notoriously difficult to achieve. This article examines health care professionals’ views on the factors influencing decision-making regarding referral to a stroke rehabilitation trial. … Conclusions Patient- and professional-related factors were the most frequent influence on clinicians’ recruitment decisions, which often had a ‘gate-keeping’ […]
Clinical Trials
Wednesday, October 5th, 2016
Stroke, 1 October 2015 Background and Purpose—The Stroke Health and Risk Education Project was a cluster-randomized, faith-based, culturally sensitive, theory-based multicomponent behavioral intervention trial to reduce key stroke risk factor behaviors in Hispanics/Latinos and European Americans. … Conclusions—This multicomponent behavioral intervention targeting stroke risk factors in predominantly Hispanics/Latinos was effective in increasing fruit and vegetable intake, reaching its […]
Clinical Trials
Wednesday, October 5th, 2016
Stroke, 1 October 2015 Background and Purpose—Central poststroke pain is a chronic neuropathic disorder that follows a stroke. Current research on its management is limited, and no review has evaluated all therapies for central poststroke pain. … Conclusions—Our findings are inconsistent with major clinical practice guidelines; the available evidence suggests no beneficial effects of any therapies that researchers […]
