Impact of Atrial Fibrillation on Stroke‐Related Healthcare Costs

J Am Heart Assoc.: November 25, 2013 Background Limited data exist on the economic implications of stroke among patients with atrial fibrillation (AF). This study assesses the impact of AF on healthcare costs associated with ischemic stroke (IS), hemorrhagic stroke (HS), or transient ischemic attack (TIA). Methods and Results A retrospective analysis of MarketScan claims data (2005‐2011) for […]

Patient-Centered Medical Homes and Oral Anticoagulation Therapy Initiation

Med Care Res Rev: November 19, 2013 Despite evidence-based guidelines, oral anticoagulation therapy (OAT) initiation is low among incident atrial fibrillation (AF) patients. Patient-centered medical homes (PCMHs) may increase access, quality, and value through coordinating care. As such, PCMHs hold potential for improving OAT initiation among AF patients. We estimated the effect of receiving care in […]

Hospitalization Rates Soar for Irregular Heartbeat, Study Finds

HealthDay Reporter: 11/18/18 Atrial fibrillation can lead to dangerous heart complications MONDAY, Nov. 18, 2013 (HealthDay News) — Hospitalizations for the most common form of irregular heartbeat nearly doubled between 1998 and 2010, and are expected to continue to soar during the current decade, researchers say. Ultimately, hospital treatment of atrial fibrillation could cost the United […]

Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation

CIRCULATIONAHA: November 18, 2013 Background—Electrical, structural, and Ca2+-handling remodeling contribute to the perpetuation/progression of atrial fibrillation (AF). Recent evidence has suggested a role for spontaneous sarcoplasmic reticulum Ca2+-release events in long-standing persistent AF, but the occurrence and mechanisms of sarcoplasmic reticulum Ca2+-release events in paroxysmal AF (pAF) are unknown. Method and Results—Right-atrial appendages from control sinus […]

Eyes Might Be Window Into Common Heart Disorder

Healthday: 11/18/13 Damage to blood vessels of the retinas and kidneys tied to higher risk for atrial fibrillation, study found MONDAY, Nov. 18, 2013 (HealthDay News) — Damage to the blood vessels of the eyes or kidneys might help identify people who are at raised risk for a common type of heart-rhythm disorder, a new study […]

Adenosine-Induced Pulmonary Vein Ectopy as a Predictor of Recurrent Atrial Fibrillation Following Pulmonary Vein Isolation

AHA: 11/15/13 Background—Adenosine (ADO) can unmask dormant pulmonary vein (PV) conduction following PV isolation. ADO can also induce ectopy in electrically silent PVs following isolation, possibly via activation of autonomic triggers. We sought to identify the implications of ADO-induced PV ectopy for atrial fibrillation (AF) recurrence following PV isolation. Methods and Results—A total of 152 patients […]

Prevalence of Silent Cerebral Ischemia in Paroxysmal and Persistent Atrial Fibrillation and Correlation With Cognitive Function

JACC: 11/19/13 Objectives  The aim of this study was to compare the prevalence of silent cerebral ischemia (SCI) and cognitive performance in patients with paroxysmal and persistent atrial fibrillation (AF) and controls in sinus rhythm. Background  Large registries have reported a similar risk for symptomatic stroke in both paroxysmal and persistent AF. The relationship among paroxysmal and persistent AF, […]

Complications of Catheter Ablation of Atrial Fibrillation: A Systematic Review

AHA: November 15, 2013 Background—Atrial fibrillation (AF) ablation is an established therapy; however, limited data is available on associated complications. This systematic review determines the incidence and potential predictors of acute complications. Methods and Results—Electronic searches were conducted in MEDLINE and EMBASE for English scientific literature up to the 18th June 2012. 2065-references were retrieved and […]

High Sensitivity Troponin I for Risk Assessment in Patients with Atrial Fibrillation: Insights from the ARISTOTLE Trial

CIRCULATIONAHA: November 13, 2013 Background—High sensitivity troponin-I (hs-TnI) measurements improves risk assessment for cardiovascular events in many clinical settings, the added value in atrial fibrillation (AF) patients has not been described. Methods and Results—At randomization hs-TnI was analyzed in 14,821 AF patients in the ARISTOTLE trial comparing apixaban with warfarin. The associations between hs-TnI concentrations and […]

Cost-Effectiveness of Oral Anticoagulants for Treatment of Atrial Fibrillation

CIRCOUTCOMES: November 12, 2013 Background—New anticoagulants may improve health outcomes in patients with atrial fibrillation, but it is unclear whether their use is cost-effective. Methods and Results—A Markov state transition was created to compare 4 therapies: dabigatran 150 mg BID, apixaban 5 mg BID, rivaroxaban 20 mg QD, and warfarin therapy. The population included those with […]

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