Atrial Fibrillation
Friday, June 7th, 2013
Eur Heart J: May 22, 2013 The terms compliance, adherence, concordance, and persistence are used to characterize important aspects of medication-taking behaviour. According to the International Society for Pharmacoeconomics and Outcomes Research Medication Compliance and Persistence Work Group, medication compliance (or adherence) is defined as ‘the extent to which a patient acts in accordance with the […]
Atrial Fibrillation
Monday, June 3rd, 2013
CIRCULATIONAHA: May 22, 2013 Background—Percutaneous left atrial appendage (LAA) occlusion and novel pharmacological therapies are now available to manage stroke risk in patients with non-valvular atrial fibrillation (NVAF). However, the cost effectiveness of LAA occlusion compared to dabigatran and warfarin in patients with NVAF is unknown. Methods and Results—Cost-utility analysis using a patient level Markov micro-simulation […]
Atrial Fibrillation
Monday, June 3rd, 2013
CIRCEP: May 16, 2013 Background—Implantable cardioverter-defibrillators (ICDs), the first-line of therapy for preventing sudden cardiac death in high-risk patients, deliver “appropriate” shocks for termination of ventricular tachycardia/fibrillation (VT/VF). A common shortcoming of ICDs is imperfect rhythm discrimination, resulting in the delivery of “inappropriate” shocks for atrial fibrillation (AF). An underexplored area for rhythm discrimination is the […]
Atrial Fibrillation
Monday, June 3rd, 2013
Chest Journal: May 9, 2013 Background When oral anticoagulation (OAC) with adjusted dose Vitamin K antagonist (VKA,) is used, the quality of anticoagulation control (as reflected by time in therapeutic range (TTR) of the International Normalised Ratio, INR) is an important determinant of thromboembolism and bleeding. Our objective was to derive a validated scheme using patient-related […]
Atrial Fibrillation
Monday, June 3rd, 2013
Circulation Journal: May 9, 2013 Atrial fibrillation (AF) is a major risk factor for stroke and the prevalence increases with age. Oral anticoagulants (OACs) are effective, but underused in elderly patients, primarily because of concerns about bleeding. Clinical study data on the efficacy (stroke/systemic embolism) and safety (bleeding events) of OACs in elderly patients with […]
Atrial Fibrillation
Wednesday, May 29th, 2013
CIRCULATIONAHA: May 22, 2013 Background—Percutaneous left atrial appendage (LAA) occlusion and novel pharmacological therapies are now available to manage stroke risk in patients with non-valvular atrial fibrillation (NVAF). However, the cost effectiveness of LAA occlusion compared to dabigatran and warfarin in patients with NVAF is unknown. Methods and Results—Cost-utility analysis using a patient level Markov micro-simulation […]
Atrial Fibrillation
Wednesday, May 29th, 2013
CIRCEP: May 17, 2013 Background—Superior vena cava (SVC) is an infrequent yet an important source of atrial fibrillation (AF). The clinical impact of adenosine triphosphate (ATP) injection on arrhythmogenic SVC has not been evaluated. Methods and Results—43 patients (59 ± 11 years; 32 males) who underwent ATP test for arrhythmogenic SVC after the electrical isolation at […]
Atrial Fibrillation
Wednesday, May 29th, 2013
CIRCEP: May 16, 2013 Background—Implantable cardioverter-defibrillators (ICDs), the first-line of therapy for preventing sudden cardiac death in high-risk patients, deliver “appropriate” shocks for termination of ventricular tachycardia/fibrillation (VT/VF). A common shortcoming of ICDs is imperfect rhythm discrimination, resulting in the delivery of “inappropriate” shocks for atrial fibrillation (AF). An underexplored area for rhythm discrimination is the […]
Atrial Fibrillation
Wednesday, May 29th, 2013
Chest Journal: May 9, 2013 Background When oral anticoagulation (OAC) with adjusted dose Vitamin K antagonist (VKA,) is used, the quality of anticoagulation control (as reflected by time in therapeutic range (TTR) of the International Normalised Ratio, INR) is an important determinant of thromboembolism and bleeding. Our objective was to derive a validated scheme using patient-related clinical parameters for […]
Atrial Fibrillation
Wednesday, May 29th, 2013
Circulation Journal: May 9, 2013 Atrial fibrillation (AF) is a major risk factor for stroke and the prevalence increases with age. Oral anticoagulants (OACs) are effective, but underused in elderly patients, primarily because of concerns about bleeding. Clinical study data on the efficacy (stroke/systemic embolism) and safety (bleeding events) of OACs in elderly patients with […]
