Atrial Fibrillation
Friday, October 5th, 2012
This study sought to determine if serum markers for collagen I and III synthesis, the carboxyl terminal peptide from pro-collagen I (PICP) and the amino terminal peptide from pro-collagen III (PIIINP), correlate with left atrial (LA) fibrosis and post-operative atrial fibrillation (AF). Background AF after cardiac surgery is associated with adverse outcomes. We recently demonstrated that […]
Atrial Fibrillation
Friday, October 5th, 2012
Translational Research in Atrial Fibrillation: A Quest for Mechanistically Based Diagnosis and Therapy Circep.ahajournals.org: September 27, 2012 Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice and is associated with increased risk of stroke, heart failure and death.1 However, currently available treatments for AF are less than satisfactory. Many drugs have been tried with […]
Atrial Fibrillation
Thursday, September 27th, 2012
Circ.ahajournals.org: 9/26/12 Atrial fibrillation is common among older persons. Catheter ablation is increasingly used in patients for whom medical therapy has failed. Methods and Results—We conducted a retrospective cohort study of all fee-for-service Medicare beneficiaries 65 years or older who underwent catheter ablation for atrial fibrillation between July 1, 2007, and December 31, 2009. The […]
Atrial Fibrillation
Thursday, September 27th, 2012
Onlinelibrary.wiley.com: 9/14/12 In patients with atrial fibrillation (AF), ventricular rate control with medications has been found to be noninferior in preventing clinical events, compared to a strategy converting patients to sinus rhythm and maintaining it with medications. Guidelines have accepted rate control as an acceptable therapeutic option. Most of the prior studies excluded patients without […]
Atrial Fibrillation
Thursday, September 27th, 2012
Eurheartj.oxfordjournals.org: 9/12/12 Atrial fibrillation (AF) is the most common sustained arrhythmia. Increased body size has been associated with AF, but the relationship is not well understood. In this study, we examined the effect of increased height on the risk of AF and explore potential mediators and implications for clinical practice. Read More
Atrial Fibrillation
Thursday, September 27th, 2012
Circoutcomes.ahajournals.org: 9/4/12 Little is known regarding the adoption of direct thrombin inhibitors in clinical practice. We examine trends in oral anticoagulation for the prevention of thromboembolism in the United States. Methods and Results—We used the IMS Health National Disease and Therapeutic Index, a nationally representative audit of office-based providers, to quantify patterns of oral anticoagulant use […]
Atrial Fibrillation
Thursday, September 27th, 2012
Physiciansweekly.com: August 30, 2012 Atrial fibrillation can be bewildering for patients, especially when they’re first diagnosed. After all, their own hearts have betrayed them, beating out of rhythm, often leaving them exhausted, frustrated, and searching for answers. Increasingly, patients are finding these answers — along with treatment options and support — through social media. For […]
Atrial Fibrillation
Friday, September 21st, 2012
Neurology: September 19, 2012 To compare the cost-effectiveness of apixaban vs warfarin for secondary stroke prevention in patients with atrial fibrillation (AF). Methods: Using standard methods, we created a Markov decision model based on the estimated cost of apixaban and data from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial […]
Atrial Fibrillation
Friday, September 21st, 2012
The American College of Physicians: September 18, 2012, Vol 157, No. 6 Question: In patients with atrial fibrillation (AF), are new oral anticoagulants effective and safe for preventing stroke and systemic embolism compared with warfarin? Review scope: Included studies compared a new, non–vitamin K antagonist oral anticoagulant with warfarin in patients with AF, had > 1 year follow-up, and […]
Atrial Fibrillation
Friday, September 21st, 2012
Atrial fibrillation (also called AFib or AF) is a quivering or irregular heartbeat (arrhythmia) that can lead to stroke and other heart-related complications. Some people refer to AF as a quivering heart. An estimated 2.7 million Americans are living with AF. Here’s how patients have described their experience: “My heart flip-flops, skips beats, and feels […]
