Familial Aggregation of Lone Atrial Fibrillation in Young Persons

onlinejacc.org: 8/27/12 This study investigated whether an individual’s risk of developing lone atrial fibrillation (AF) before age 60 years is associated with lone AF in relatives. Background  Genetic factors may play a role in the development of lone AF. Methods  Using Danish national registers, a cohort was established of ∼4 million persons born between 1950 and 2008, and […]

European Society of Cardiology updates AF treatment Guidelines–Six major focus points

theheart.org: Aug 26, 2012 The treatment of atrial fibrillation is a fast-moving field. It’s a good thing, because the prevalence of the disease continues to increase. In Europe, estimates are that AF burdens almost 2% of the general population. In the past two years, enough data have come available to warrant an update to the 2010 […]

Fertile women with obesity more likely to develop atrial fibrillation

News-medical.net:  August 26, 2012 Obesity triggers atrial fibrillation in fertile women, according to research presented today at the ESC Congress 2012 by Dr Deniz Karasoy from Denmark. Atrial fibrillation and obesity are among the largest public health related challenges in the western world today. Atrial fibrillation is the commonest heart rhythm disorder and is associated with increased mortality and […]

Triple antithrombotic therapy in patients with atrial fibrillation who have undergone percutaneous coronary intervention with stent implantation

American Journal of Health-System: 9/1/12 The efficacy and safety of triple antithrombotic therapy in patients with atrial fibrillation (AF) who undergo percutaneous coronary intervention (PCI) with stent implantation are reviewed. Summary A systematic literature search of PubMed, EMBASE, and International Pharmaceutical Abstracts identified a total of 10 cohort studies and one meta-analysis investigating triple antithrombotic therapy in […]

Electrophysiological and Hemodynamic Characteristics Associated With Obesity in Patients With Atrial Fibrillation

American College of Cardiology Foundation: 8/28/12 The authors sought to characterize the left atrial (LA) and pulmonary vein (PV) electrophysiological and hemodynamic features in obese patients with atrial fibrillation (AF). Background  Obesity is associated with increased risk for AF. Methods  A total of 63 consecutive patients with AF who had normal left ventricular (LV) ejection fraction and who […]

Arrhythmia and Electrophysiology

J Am Heart Assoc.: 8/17/12 Atrial fibrillation (AF) and chronic kidney disease (CKD) are prevalent in the elderly and are independently associated with increased risk of death. We evaluated risk of incident AF with advancing CKD and examined the mortality rate associated with CKD after incident AF in elderly patients. Methods and Results This retrospective cohort study […]

Arterial hypertension and atrial fibrillation: Selecting antihypertensive therapy

Sciencedirect.com: 8/17/12 Arterial hypertension is the most common cardiovascular disease. Atrial fibrillation in hypertension has frequent occurrence, which increases with age. While the mechanism underlying the development of atrial fibrillation is complex, hypertension is considered one of the main pathogenic factors resulting in this arrhythmia. Hypertension is also the key risk factor for stroke, with the […]

Recent Insights into the Mechanisms Underlying Persistent Atrial Fibrillation

innovationsincrm.com: 8/1/12 Atrial fibrillation (AF) is a gradually progressive atrial disease process manifesting as the most common heart rhythm disorder. Early in its clinical course, the arrhythmia may be frequently triggered by rapid firing of impulses from focal sources. Almost all cases of true paroxysmal AF are caused by ectopic signals that originate in the thoracic […]

Stroke and Bleeding in Atrial Fibrillation with Chronic Kidney Disease

Nejm.org: August 16, 2012 Both atrial fibrillation and chronic kidney disease increase the risk of stroke and systemic thromboembolism. However, these risks, and the effects of antithrombotic treatment, have not been thoroughly investigated in patients with both conditions. Using Danish national registries, we identified all patients discharged from the hospital with a diagnosis of nonvalvular atrial […]

Factors Associated With the Epidemic of Hospitalizations Due to Atrial Fibrillation

Ajconline.org: 8/10/12 This study was presented in part at the European Society of Cardiology Congress, Stockholm, Sweden, August 2010 and published in abstract form (Eur Heart J 2010;31:S166). Recent reports have described that hospitalizations for atrial fibrillation (AF) are continuing to increase. Given that hospitalizations are responsible for most of the economic burden associated with AF, the […]

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